Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs.
about
Crystal Structures of Three Classes of Non-Steroidal Anti-Inflammatory Drugs in Complex with Aldo-Keto Reductase 1C3Structure of AKR1C3 with 3-phenoxybenzoic acid boundModulation of cell metabolic pathways and oxidative stress signaling contribute to acquired melphalan resistance in multiple myeloma cellsLack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancersModulated expression of genes encoding estrogen metabolizing enzymes by G1-phase cyclin-dependent kinases 6 and 4 in human breast cancer cells.Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism.Inhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3): overview and structural insights.Selective AKR1C3 inhibitors do not recapitulate the anti-leukaemic activities of the pan-AKR1C inhibitor medroxyprogesterone acetate.Screening baccharin analogs as selective inhibitors against type 5 17β-hydroxysteroid dehydrogenase (AKR1C3).Non steroidal anti-inflammatory drug use and levels of oestrogens and androgens in men.Enhanced 4-hydroxynonenal resistance in KEAP1 silenced human colon cancer cellsThe tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes.AKR1C3 as a target in castrate resistant prostate cancerNew agents and strategies for the hormonal treatment of castration-resistant prostate cancer.Human aldo-keto reductases: structure, substrate specificity and roles in tumorigenesis.Discovery of (R)-2-(6-Methoxynaphthalen-2-yl)butanoic Acid as a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor.Induction of neoplastic transformation by ectopic expression of human aldo-keto reductase 1C isoforms in NIH3T3 cells.Conservative treatment of deep infiltrating endometriosis: review of existing options.Aldo-Keto Reductases Mediated Cytotoxicity of 2-Deoxyglucose: A Novel Anticancer Mechanism.Stereospecific Metabolism of R- and S-Warfarin by Human Hepatic Cytosolic Reductases.
P2860
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P2860
Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs.
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Type 5 17beta-hydroxysteroid d ...... nti-inflammatory drug analogs.
@ast
Type 5 17beta-hydroxysteroid d ...... nti-inflammatory drug analogs.
@en
Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase
@nl
type
label
Type 5 17beta-hydroxysteroid d ...... nti-inflammatory drug analogs.
@ast
Type 5 17beta-hydroxysteroid d ...... nti-inflammatory drug analogs.
@en
Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase
@nl
prefLabel
Type 5 17beta-hydroxysteroid d ...... nti-inflammatory drug analogs.
@ast
Type 5 17beta-hydroxysteroid d ...... nti-inflammatory drug analogs.
@en
Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase
@nl
P2860
P1476
Type 5 17beta-hydroxysteroid d ...... anti-inflammatory drug analogs
@en
P2093
Michael C Byrns
P2860
P304
P356
10.1016/J.CBI.2008.10.024
P577
2008-11-01T00:00:00Z