Structure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility.
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The Intracellular Loop of the Glycine Receptor: It's not all about the SizeMutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystalsA locally closed conformation of a bacterial pentameric proton-gated ion channelGating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallographyCrystal structures of a pentameric ligand-gated ion channel provide a mechanism for activationX-ray structure of the human α4β2 nicotinic receptorMolecular mechanism for the dual alcohol modulation of Cys-loop receptorsSite-directed spin labeling reveals pentameric ligand-gated ion channel gating motionsPropofol binding to the resting state of the gloeobacter violaceus ligand-gated ion channel (GLIC) induces structural changes in the inter- and intrasubunit transmembrane domain (TMD) cavitiesDelineating the extracellular water-accessible surface of the proton-coupled folate transporter.Mapping the membrane topography of the TH6-TH7 segment of the diphtheria toxin T-domain channel.Macroscopic kinetics of pentameric ligand gated ion channels: comparisons between two prokaryotic channels and one eukaryotic channel.Structural basis for alcohol modulation of a pentameric ligand-gated ion channelEngineering a prokaryotic Cys-loop receptor with a third functional domain.Conformational Changes Underlying Desensitization of the Pentameric Ligand-Gated Ion Channel ELIC.The atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold.Intramembrane proton binding site linked to activation of bacterial pentameric ion channel.The pharmacological profile of ELIC, a prokaryotic GABA-gated receptorGating-induced conformational rearrangement of the γ-aminobutyric acid type A receptor β-α subunit interface in the membrane-spanning domainA Cysteine Substitution Probes β3H267 Interactions with Propofol and Other Potent Anesthetics in α1β3γ2L γ-Aminobutyric Acid Type A ReceptorsTheory and simulation of ion conduction in the pentameric GLIC channelExperimental determination of the vertical alignment between the second and third transmembrane segments of muscle nicotinic acetylcholine receptorsInhibition versus potentiation of ligand-gated ion channels can be altered by a single mutation that moves ligands between intra- and intersubunit sitesCysteine substitutions define etomidate binding and gating linkages in the α-M1 domain of γ-aminobutyric acid type A (GABAA) receptorsIntermediate closed state for glycine receptor function revealed by cysteine cross-linking.A gating mechanism of pentameric ligand-gated ion channels.Using molecular dynamics to elucidate the structural basis for function in pLGICsCrystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel.An outline of desensitization in pentameric ligand-gated ion channel receptors.EPR Studies of Gating Mechanisms in Ion Channels.Cys-loop receptor channel blockers also block GLIC.Probing residues in the pore-forming (M2) domain of the Cys-loop receptor homologue GLIC reveals some unusual features.Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC).Desensitization mechanism in prokaryotic ligand-gated ion channelConformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC)Chasing the open-state structure of pentameric ligand-gated ion channels.
P2860
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P2860
Structure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structure of the M2 transmembr ...... ituted cysteine accessibility.
@ast
Structure of the M2 transmembr ...... ituted cysteine accessibility.
@en
Structure of the M2 transmembr ...... ituted cysteine accessibility.
@nl
type
label
Structure of the M2 transmembr ...... ituted cysteine accessibility.
@ast
Structure of the M2 transmembr ...... ituted cysteine accessibility.
@en
Structure of the M2 transmembr ...... ituted cysteine accessibility.
@nl
prefLabel
Structure of the M2 transmembr ...... ituted cysteine accessibility.
@ast
Structure of the M2 transmembr ...... ituted cysteine accessibility.
@en
Structure of the M2 transmembr ...... ituted cysteine accessibility.
@nl
P2860
P356
P1476
Structure of the M2 transmembr ...... tituted cysteine accessibility
@en
P2093
Rishi B Parikh
P2860
P304
14098-14109
P356
10.1074/JBC.M111.221895
P407
P577
2011-03-01T00:00:00Z