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pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epitheliaPolyomavirus-associated Trichodysplasia spinulosa involves hyperproliferation, pRB phosphorylation and upregulation of p16 and p21The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cyclePhosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damageMethylation of the retinoblastoma tumor suppressor by SMYD2p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosisTwo ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stressp53 Stabilization and accumulation induced by human vaccinia-related kinase 1Proapoptotic function of the retinoblastoma tumor suppressor proteinFeedback circuit among INK4 tumor suppressors constrains human glioblastoma developmentSuppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicityPlk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progressionNegative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes.Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic miceFoxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressorMolecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancersRemodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and agingCrystal structure of human CDK4 in complex with a D-type cyclinDifferential gene expression of p27Kip1 and Rb knockout pituitary tumors associated with altered growth and angiogenesisMethylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytomaGenetic perspective of retinoblastoma: From present to futureMouse models for radiation-induced cancersThe Modulation of Apoptotic Pathways by GammaherpesvirusesChemoprevention of Breast Cancer by Dietary PolyphenolsDNA repair and aging: the impact of the p53 familyTargeted cancer therapy with ribosome biogenesis inhibitors: a real possibility?Mouse models for efficacy testing of agents against radiation carcinogenesis—a literature reviewMolecular mechanisms underlying RB protein functionDisruptive chemicals, senescence and immortalityCoordinated regulation of intestinal functions in C. elegans by LIN-35/Rb and SLR-2Crystal structure of the homolog of the oncoprotein gankyrin, an interactor of Rb and CDK4/6A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.The Impact of Genomic Profiling for Novel Cancer Therapy--Recent Progress in Non-Small Cell Lung CancerMolecular targets in urothelial cancer: detection, treatment, and animal models of bladder cancerDisruptive environmental chemicals and cellular mechanisms that confer resistance to cell deathThe potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signallingIFI16 as a negative regulator in the regulation of p53 and p21(Waf1)Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancerAberrant regulation of survivin by the RB/E2F family of proteins
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The RB and p53 pathways in cancer.
@ast
The RB and p53 pathways in cancer.
@en
The RB and p53 pathways in cancer.
@nl
type
label
The RB and p53 pathways in cancer.
@ast
The RB and p53 pathways in cancer.
@en
The RB and p53 pathways in cancer.
@nl
prefLabel
The RB and p53 pathways in cancer.
@ast
The RB and p53 pathways in cancer.
@en
The RB and p53 pathways in cancer.
@nl
P1433
P1476
The RB and p53 pathways in cancer.
@en
P2093
Charles J Sherr
Frank McCormick
P304
P356
10.1016/S1535-6108(02)00102-2
P577
2002-08-01T00:00:00Z