Novel protective properties of IGFBP-3 result in enhanced pericyte ensheathment, reduced microglial activation, increased microglial apoptosis, and neuronal protection after ischemic retinal injury.
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An ocular view of the IGF-IGFBP systemCompound 49b Restores Retinal Thickness and Reduces Degenerate Capillaries in the Rat Retina following Ischemia/ReperfusionPericytes derived from adipose-derived stem cells protect against retinal vasculopathy.Promoting vascular repair in the retina: can stem/progenitor cells help?Regulation of retinal endothelial cell apoptosis through activation of the IGFBP-3 receptor.Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).Inflammation in the pathogenesis of microvascular complications in diabetes.Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3.IGFBP-3 inhibits cytokine-induced insulin resistance and early manifestations of atherosclerosisPioglitazone restores IGFBP-3 levels through DNA PK in retinal endothelial cells cultured in hyperglycemic conditions.Increase of zinc finger protein 179 in response to CCAAT/enhancer binding protein delta conferring an antiapoptotic effect in astrocytes of Alzheimer's disease.IGFBP-3 inhibits TNF-α production and TNFR-2 signaling to protect against retinal endothelial cell apoptosis.Loss of survival factors and activation of inflammatory cascades in brain sympathetic centers in type 1 diabetic mice.Compound 49b prevents diabetes-induced apoptosis through increased IGFBP-3 levelsMEF2C ablation in endothelial cells reduces retinal vessel loss and suppresses pathologic retinal neovascularization in oxygen-induced retinopathyInsulin-like growth factor binding protein-3 inhibits monocyte adhesion to retinal endothelial cells in high glucose conditions.IGFBP-3 and TNF-α regulate retinal endothelial cell apoptosis.Nutrition, insulin-like growth factor-1 and retinopathy of prematurityGene expression of IGF1, IGF1R, and IGFBP3 in epiretinal membranes of patients with proliferative diabetic retinopathy: preliminary study.Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option?IGFBP-3 reduces eNOS and PKCzeta phosphorylation, leading to lowered VEGF levels.Treatment with polyamine oxidase inhibitor reduces microglial activation and limits vascular injury in ischemic retinopathy.Diabetes changes expression of genes related to glutamate neurotransmission and transport in the Long-Evans rat retina.Relationship between Pericytes and Endothelial Cells in Retinal Neovascularization: A Histological and Immunofluorescent Study of Retinal Angiogenesis.Unique and shared inflammatory profiles of human brain endothelia and pericytes.The progress of prophylactic treatment in retinopathy of prematurity.
P2860
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P2860
Novel protective properties of IGFBP-3 result in enhanced pericyte ensheathment, reduced microglial activation, increased microglial apoptosis, and neuronal protection after ischemic retinal injury.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Novel protective properties of ...... after ischemic retinal injury.
@ast
Novel protective properties of ...... after ischemic retinal injury.
@en
Novel protective properties of ...... after ischemic retinal injury.
@nl
type
label
Novel protective properties of ...... after ischemic retinal injury.
@ast
Novel protective properties of ...... after ischemic retinal injury.
@en
Novel protective properties of ...... after ischemic retinal injury.
@nl
prefLabel
Novel protective properties of ...... after ischemic retinal injury.
@ast
Novel protective properties of ...... after ischemic retinal injury.
@en
Novel protective properties of ...... after ischemic retinal injury.
@nl
P2093
P2860
P1476
Novel protective properties of ...... after ischemic retinal injury
@en
P2093
Evan McFarland
Jennifer L Kielczewski
Lynn C Shaw
Maria B Grant
Robert N Mames
Sergio Li Calzi
Tom A Gardiner
P2860
P304
P356
10.1016/J.AJPATH.2010.12.031
P407
P577
2011-04-01T00:00:00Z