Different topoisomerase II antitumor drugs direct similar specific long-range fragmentation of an amplified c-MYC gene locus in living cells and in high-salt-extracted nuclei.
about
Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activitiesTranscriptional consequences of topoisomerase inhibitionInduction of transcription within chromosomal DNA loops flanked by MAR elements causes an association of loop DNA with the nuclear matrixTwo MAR DNA-binding proteins of the pea nuclear matrix identify a new class of DNA-binding proteins.Determination of the in vivo structural DNA loop organization in the genomic region of the rat albumin locus by means of a topological approach.Visualization of individual DNA loops and a map of loop domains in the human dystrophin gene.Chromatin loop domain organization within the 4q35 locus in facioscapulohumeral dystrophy patients versus normal human myoblasts.Ribonucleoprotein-masked nicks at 50-kbp intervals in the eukaryotic genomic DNA.A nuclear matrix attachment site in the 4q35 locus has an enhancer-blocking activity in vivo: implications for the facio-scapulo-humeral dystrophy.Mapping of genomic DNA loop organization in a 500-kilobase region of the Drosophila X chromosome by the topoisomerase II-mediated DNA loop excision protocol.Induction of DNA replication by transcription in the region upstream of the human c-myc gene in a model replication system.Mapping of the nuclear matrix-bound chromatin hubs by a new M3C experimental procedure.Mapping of a human centromere onto the DNA by topoisomerase II cleavageDual mechanism of daunorubicin-induced cell death in both sensitive and MDR-resistant HL-60 cells.Large-scale fragmentation of mammalian DNA in the course of apoptosis proceeds via excision of chromosomal DNA loops and their oligomers.Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IINon-random features of loop-size chromatin fragmentation.Topoisomerase IIB and an extracellular nuclease interact to digest sperm DNA in an apoptotic-like manner.
P2860
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P2860
Different topoisomerase II antitumor drugs direct similar specific long-range fragmentation of an amplified c-MYC gene locus in living cells and in high-salt-extracted nuclei.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Different topoisomerase II ant ...... in high-salt-extracted nuclei.
@ast
Different topoisomerase II ant ...... in high-salt-extracted nuclei.
@en
Different topoisomerase II ant ...... in high-salt-extracted nuclei.
@nl
type
label
Different topoisomerase II ant ...... in high-salt-extracted nuclei.
@ast
Different topoisomerase II ant ...... in high-salt-extracted nuclei.
@en
Different topoisomerase II ant ...... in high-salt-extracted nuclei.
@nl
prefLabel
Different topoisomerase II ant ...... in high-salt-extracted nuclei.
@ast
Different topoisomerase II ant ...... in high-salt-extracted nuclei.
@en
Different topoisomerase II ant ...... in high-salt-extracted nuclei.
@nl
P2860
P50
P356
P1476
Different topoisomerase II ant ...... in high-salt-extracted nuclei
@en
P2093
P2860
P304
P356
10.1073/PNAS.92.1.102
P407
P577
1995-01-01T00:00:00Z