about
Challenges to the clinical application of pluripotent stem cells: towards genomic and functional stabilityGenome-editing tools for stem cell biologyCellular reprogramming: a small molecule perspectiveConcise review: Generation of neurons from somatic cells of healthy individuals and neurological patients through induced pluripotency or direct conversionTherapeutic Potential of Stem Cells Strategy for Cardiovascular DiseasesInduced Stem Cells as a Novel Multiple Sclerosis TherapyAbnormal dosage of ultraconserved elements is highly disfavored in healthy cells but not cancer cellsMitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrationsReversible mitochondrial DNA accumulation in nuclei of pluripotent stem cellsModified lentiviral LTRs allow Flp recombinase-mediated cassette exchange and in vivo tracing of "factor-free" induced pluripotent stem cells.Understanding the roadmaps to induced pluripotency.Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotencyTherapeutic opportunities: telomere maintenance in inducible pluripotent stem cells.Passage number is a major contributor to genomic structural variations in mouse iPSCs.Induced pluripotent stem cells--opportunities for disease modelling and drug discovery.A model of cancer stem cells derived from mouse induced pluripotent stem cells.Context-dependent enhancement of induced pluripotent stem cell reprogramming by silencing Puma.Mutation frequency dynamics in HPRT locus in culture-adapted human embryonic stem cells and induced pluripotent stem cells correspond to their differentiated counterpartsGenomic instability in iPS: time for a breakModeling stem cell induction processes.Investigation of hepatoprotective activity of induced pluripotent stem cells in the mouse model of liver injury.Clinical therapy using iPSCs: hopes and challengesInduced pluripotent stem cells are sensitive to DNA damage.Aneuploidy is permissive for hepatocyte-like cell differentiation from human induced pluripotent stem cells.Whole genome RNAi screens reveal a critical role of REV3 in coping with replication stress.Telomere dynamics in induced pluripotent stem cells: Potentials for human disease modeling.Human amniotic fluid stem cells as a model for functional studies of genes involved in human genetic diseases or oncogenesis.A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells.Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells.Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues.Mouse Lymphoblastic Leukemias Induced by Aberrant Prdm14 Expression Demonstrate Widespread Copy Number Alterations Also Found in Human ALL.Assessing the risks of genotoxicity in the therapeutic development of induced pluripotent stem cellsEmbryonic stem cells and inducible pluripotent stem cells: two faces of the same coin?Stem cell therapy for cardiovascular disease: the demise of alchemy and rise of pharmacology.Amniotic fluid stem cell-based models to study the effects of gene mutations and toxicants on male germ cell formationHuman induced pluripotent stem cells from basic research to potential clinical applications in cancerAntioxidant supplementation reduces genomic aberrations in human induced pluripotent stem cells.Embryonic stem cells or induced pluripotent stem cells? A DNA integrity perspective.Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stressRegulation of self-renewal in normal and cancer stem cells.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Genomic instability in induced stem cells
@ast
Genomic instability in induced stem cells
@en
Genomic instability in induced stem cells
@nl
type
label
Genomic instability in induced stem cells
@ast
Genomic instability in induced stem cells
@en
Genomic instability in induced stem cells
@nl
prefLabel
Genomic instability in induced stem cells
@ast
Genomic instability in induced stem cells
@en
Genomic instability in induced stem cells
@nl
P2093
P2860
P356
P1476
Genomic instability in induced stem cells
@en
P2093
A Dereli-Öz
G Van Houwe
P G Pelicci
P2860
P2888
P304
P356
10.1038/CDD.2011.9
P577
2011-02-11T00:00:00Z
P5875
P6179
1039195900