Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization
about
Cellular traction stresses increase with increasing metastatic potentialImpact of dimensionality and network disruption on microrheology of cancer cells in 3D environmentsDynamic functions of RhoA in tumor cell migration and invasionActomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growthPodoplanin - a small glycoprotein with many facesCapturing relevant extracellular matrices for investigating cell migrationCell polarity signaling in the plasticity of cancer cell invasivenessMechanosensing via cell-matrix adhesions in 3D microenvironmentsRho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunitiesAt the leading edge of three-dimensional cell migrationPhysical biology in cancer. 4. Physical cues guide tumor cell adhesion and migrationPhysical biology in cancer. 5. The rocky road of metastasis: the role of cytoskeletal mechanics in cell migratory response to 3D matrix topographyWhy the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkersRho GTPases in collective cell migrationTumor cell migration in complex microenvironmentsMesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-βChemotaxis of cell populations through confined spaces at single-cell resolutionRegulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulationLocal 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions.A Combined In Vitro Imaging and Multi-Scale Modeling System for Studying the Role of Cell Matrix Interactions in Cutaneous Wound HealingCorneal Fibroblast Migration Patterns During Intrastromal Wound Healing Correlate With ECM Structure and Alignment.Mechanical decision trees for investigating and modulating single-cell cancer invasion dynamicsBi-directional signaling: extracellular matrix and integrin regulation of breast tumor progressionSchwann cells promote endothelial cell migrationSingle-Cell Migration in Complex Microenvironments: Mechanics and Signaling DynamicsRandom versus directionally persistent cell migrationPlasticity of cell migration: a multiscale tuning modelMatrix microarchitecture and myosin II determine adhesion in 3D matrices.Force generated by actomyosin contraction builds bridges between adhesive contacts.Restriction of receptor movement alters cellular response: physical force sensing by EphA2.Rho Kinase Regulation of Fibroblast Migratory Mechanics in Fibrillar Collagen Matrices.Corneal stromal cells use both high- and low-contractility migration mechanisms in 3-D collagen matrices.Microfabricated collagen tracks facilitate single cell metastatic invasion in 3DCCM1-ICAP-1 complex controls β1 integrin-dependent endothelial contractility and fibronectin remodelingA bioengineered heterotypic stroma-cancer microenvironment model to study pancreatic ductal adenocarcinoma.Rapid disorganization of mechanically interacting systems of mammary acini.Preferential, enhanced breast cancer cell migration on biomimetic electrospun nanofiber 'cell highways'Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracksSuperstatistical analysis and modelling of heterogeneous random walks.Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices.
P2860
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P2860
Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Contact guidance mediated thre ...... ependent matrix reorganization
@ast
Contact guidance mediated thre ...... ependent matrix reorganization
@en
Contact guidance mediated thre ...... ependent matrix reorganization
@nl
type
label
Contact guidance mediated thre ...... ependent matrix reorganization
@ast
Contact guidance mediated thre ...... ependent matrix reorganization
@en
Contact guidance mediated thre ...... ependent matrix reorganization
@nl
prefLabel
Contact guidance mediated thre ...... ependent matrix reorganization
@ast
Contact guidance mediated thre ...... ependent matrix reorganization
@en
Contact guidance mediated thre ...... ependent matrix reorganization
@nl
P2093
P2860
P1433
P1476
Contact guidance mediated thre ...... ependent matrix reorganization
@en
P2093
David R Inman
Patricia J Keely
Steven M Trier
P2860
P304
P356
10.1529/BIOPHYSJ.108.133116
P407
P577
2008-09-05T00:00:00Z