Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations
about
Breast enlargement in Malawian males on the standard first-line antiretroviral therapy regimen: Case reports and review of the literaturePharmacokinetic, Pharmacogenetic, and Other Factors Influencing CNS Penetration of AntiretroviralsEffect of CYP2B6 Gene Polymorphisms on Efavirenz Plasma Concentrations in Chinese Patients with HIV InfectionRecruitment of Yoruba families from Nigeria for genetic research: experience from a multisite keloid study.Pharmacogenetic-based efavirenz dose modification: suggestions for an African population and the different CYP2B6 genotypesHigh CYP2A6 enzyme activity as measured by a caffeine test and unique distribution of CYP2A6 variant alleles in Ethiopian population.Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant womenFrequencies of two functionally significant SNPs and their haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in six ethnic groups of Pakistani population.Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin-based combinations.Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study.Clinical and pharmacogenomic implications of genetic variation in a Southern Ethiopian population.Cytochrome P450 2B6 genetic variants are associated with plasma nevirapine levels and clinical response in HIV-1 infected Kenyan women: a prospective cohort study.The influence of nevirapine and efavirenz-based anti-retroviral therapy on the pharmacokinetics of lumefantrine and anti-malarial dose recommendation in HIV-malaria co-treatmentPharmacogenetics of plasma efavirenz exposure in HIV-infected adults and children in South Africa.Pharmacogenomics Implications of Using Herbal Medicinal Plants on African Populations in Health TransitionGenome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity.An Expanded Analysis of Pharmacogenetics Determinants of Efavirenz Response that Includes 3'-UTR Single Nucleotide Polymorphisms among Black South African HIV/AIDS PatientsCYP2B6*6 and CYP2B6*18 Predict Long-Term Efavirenz Exposure Measured in Hair Samples in HIV-Positive South African WomenPharmacogenomic implications of the evolutionary history of infectious diseases in AfricaCytochrome P450 pharmacogenetics in African populations: implications for public health.Pharmacogenetics of CYP2B6, CYP2A6 and UGT2B7 in HIV treatment in African populations: focus on efavirenz and nevirapine.Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature.Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs.A review of trials investigating efavirenz-induced neuropsychiatric side effects and the implications.Population Pharmacokinetic Model Linking Plasma and Peripheral Blood Mononuclear Cell Concentrations of Efavirenz and Its Metabolite, 8-Hydroxy-Efavirenz, in HIV Patients.CYP2B6 genotype-based efavirenz dose recommendations during rifampicin-based antituberculosis cotreatment for a sub-Saharan Africa population.CYP2B6 genotype, but not rifampicin-based anti-TB cotreatments, explains variability in long-term efavirenz plasma exposure.Genetic Polymorphisms Affecting the Pharmacokinetics of Antiretroviral Drugs.Cytochrome 2B6 polymorphism and efavirenz-induced central nervous system symptoms : a substudy of the ANRS ALIZE trial.Role of Cytochrome P450 2B6 Pharmacogenomics in Determining Efavirenz-Mediated Central Nervous System Toxicity, Treatment Outcomes, and Dosage Adjustments in Patients with Human Immunodeficiency Virus Infection.Is there a need to increase the dose of efavirenz during concomitant rifampicin-based antituberculosis therapy in sub-Saharan Africa? The HIV-TB pharmagene study.Consequences of a Chronic Exposure of Cultured Brain Astrocytes to the Anti-Retroviral Drug Efavirenz and its Primary Metabolite 8-Hydroxy Efavirenz.Genetic variants in CYP2B6 and CYP2A6 explain interindividual variation in efavirenz plasma concentrations of HIV-infected children with diverse ethnic origin.Long-Term Effect of Rifampicin-Based Anti-TB Regimen Coadministration on the Pharmacokinetic Parameters of Efavirenz and 8-Hydroxy-Efavirenz in Ethiopian Patients.CYP2B6*6 genotype and high efavirenz plasma concentration but not nevirapine are associated with low lumefantrine plasma exposure and poor treatment response in HIV-malaria-coinfected patients.Pharmacokinetics of rosuvastatin in 30 healthy Zimbabwean individuals of African ancestry.Pharmacogenetic considerations for HIV treatment in different ethnicities: an update.Disease burden and the role of pharmacogenomics in African populations.Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype
P2860
Q26771622-F8340F6E-6C35-4E28-8298-F1D81BA8C814Q28069383-71A43C73-10B2-450E-A29D-E1911F3CBD41Q28548638-2BFF4A92-FF4D-4EF1-8F84-6E288F26028FQ30847208-ADB3A741-8FE8-4096-B5FE-CF5C3D61F08BQ31150044-BFD1AFED-0657-450B-A68F-BF57F85070EBQ33861268-E5C7775D-E848-42F4-A98E-DDA4A97BA502Q33869119-D4A18FC1-3C77-4C14-BA7D-1F859DDD6DD0Q34065757-A7893495-D4C0-474F-B325-ABE9A1554742Q34491448-E33804D4-B32E-4691-9C3E-8A08FCBC46CCQ34756398-7C952E27-9270-4C86-A5F7-88736DFDB599Q34778035-9DFFE7A2-D352-4CEB-B9B4-33251E4C9486Q35426496-BC1D670F-35AB-45EE-A936-FC1B19450EA4Q35583982-2BFE5DBD-829A-43F3-9AF5-B6DE7FD2DE7EQ35846143-E7163C1B-5BC6-4745-AF39-DCB86E8DB54FQ36105822-5B8C3ABD-F561-4190-B746-EE7FF75AAE83Q36145491-767F32EB-90F4-436F-BFB5-879BB10CDA8DQ36437792-B6AB2210-55E3-4DEE-AFD2-ED427048D320Q36966640-0CD2F81B-68B7-435B-80F6-8A88529FDF8AQ37737731-AF6EBC2A-90A3-4AA9-BFAE-86F8699935B1Q38192688-BE360D8B-57FD-46DC-8006-88278AB6408FQ38267710-6683CDA9-E493-4341-A79E-C93387BC64F0Q38414396-50B50859-15B2-40B1-AD64-5D91A655C39FQ38733565-C621E07A-3AA3-49E0-87F0-BC9E6DD2B510Q38743628-13C092CB-75E9-487B-9239-3491BFB2E46BQ38755666-EF03FF9B-6D4E-4823-A46C-BC89E4D3A5E5Q38855121-65B623B3-A42F-46A8-B063-0E6E4B347B03Q38861140-51D42862-D25F-401B-9719-3CD7745681D2Q38957969-204F1B40-E667-4365-885C-F8F2839A3C83Q38987587-E0ACED3C-251A-47C4-83B4-6AC5F69B8586Q38990321-4AA745D8-B889-4A48-AFAB-A04FAE8DD74DQ39039468-5C24EB7B-C5C4-4D7C-8FC8-795698D502EBQ39364925-BC1803B1-27BF-47A4-ACDF-F045EAD98DEFQ40050910-8030B34F-4D68-4B2C-B9F7-09A6BEE601B0Q40694902-D9246B2B-6197-4B75-95D9-57C26B9E07A4Q41240864-F112F283-0022-40D0-9B6D-AF25DED8FC24Q42562160-E715B63E-250F-4300-9539-002C12205118Q47906608-AF00CD62-B0CC-44C6-90F8-CD3CA4CA4B86Q54935902-E5DCE34A-3ACE-44B3-9A8E-42A5F63E64B9Q58612379-5CB780C3-2FAB-4C93-83FC-B2167FB649B9
P2860
Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Importance of ethnicity, CYP2B ...... sub-Saharan Africa populations
@ast
Importance of ethnicity, CYP2B ...... sub-Saharan Africa populations
@en
Importance of ethnicity, CYP2B ...... sub-Saharan Africa populations
@nl
type
label
Importance of ethnicity, CYP2B ...... sub-Saharan Africa populations
@ast
Importance of ethnicity, CYP2B ...... sub-Saharan Africa populations
@en
Importance of ethnicity, CYP2B ...... sub-Saharan Africa populations
@nl
prefLabel
Importance of ethnicity, CYP2B ...... sub-Saharan Africa populations
@ast
Importance of ethnicity, CYP2B ...... sub-Saharan Africa populations
@en
Importance of ethnicity, CYP2B ...... sub-Saharan Africa populations
@nl
P2093
P2860
P50
P1433
P1476
Importance of ethnicity, CYP2B ...... sub-Saharan Africa populations
@en
P2093
Abiy Habtewold
Eliford Ngaimisi
Ferdinand Mugusi
Getachew Aderaye
Getnet Yimer
Juergen Burhenne
Klaus-Dieter Riedel
Mohammed Janabi
Omary Minzi
Sabina Mugusi
P2860
P304
P356
10.1371/JOURNAL.PONE.0067946
P407
P577
2013-07-05T00:00:00Z