Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
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Rho GTPases regulate PRK2/PKN2 to control entry into mitosis and exit from cytokinesis.Novel Insights into the Roles of Rho Kinase in CancerAurora-A kinase is essential for bipolar spindle formation and early developmentConditional Aurora A deficiency differentially affects early mouse embryo patterningThe Aurora-A inhibitor MLN8237 affects multiple mitotic processes and induces dose-dependent mitotic abnormalities and aneuploidyBreast cancer biomarker discovery in the functional genomic age: a systematic review of 42 gene expression signatures.Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle.Aurora A, mitotic entry, and spindle bipolarity.Apoptosis regulation in tetraploid cancer cells.Aurora-A kinase-inactive mutants disrupt the interaction with Ajuba and cause defects in mitotic spindle formation and G2/M phase arrest in HeLa cells.Aurora kinase A has a significant role as a therapeutic target and clinical biomarker in endometrial cancer.Aurora kinase A controls meiosis I progression in mouse oocytes.Predictive biomarkers of sensitivity to the aurora and angiogenic kinase inhibitor ENMD-2076 in preclinical breast cancer models.Interdependence of cell attachment and cell cycle signaling.Depletion of Aurora A leads to upregulation of FoxO1 to induce cell cycle arrest in hepatocellular carcinoma cells.Rho kinase in the regulation of cell death and survival.Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progressionRho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil.Activation of the human FP prostanoid receptor disrupts mitosis progression and generates aneuploidy and polyploidy.Aurora A is a negative prognostic factor and a new therapeutic target in human neuroblastoma.Bioactive compounds of Eriocaulon sieboldianum blocking proliferation and inducing apoptosis of HepG2 cells might be involved in Aurora kinase inhibition.Capsaicin induces apoptosis of cisplatin-resistant stomach cancer cells by causing degradation of cisplatin-inducible Aurora-A protein.Transcriptional regulation of serine/threonine kinase-15 (STK15) expression by hypoxia and HIF-1.Hypoxia-inducible enhancer/alpha-fetoprotein promoter-driven RNA interference targeting STK15 suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.Inactivation of Rho GTPases with Clostridium difficile toxin B impairs centrosomal activation of Aurora-A in G2/M transition of HeLa cellsCdk1 activity is required for mitotic activation of aurora A during G2/M transition of human cells.Astrin regulates Aurora-A localization.Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.
P2860
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P2860
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
@ast
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
@en
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
@nl
type
label
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
@ast
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
@en
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
@nl
prefLabel
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
@ast
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
@en
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
@nl
P2860
P356
P1476
Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.
@en
P2093
P2860
P304
P356
10.1073/PNAS.0308484101
P407
P577
2004-06-03T00:00:00Z