Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes.
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Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistanceIs the Mouse a Good Model of Human PPARγ-Related Metabolic Diseases?Role of Transcription Factors in Steatohepatitis and Hypertension after Ethanol: The Epicenter of MetabolismHydroxycinnamic acid derivatives: a potential class of natural compounds for the management of lipid metabolism and obesityInteractions between Myc and Mediators of Inflammation in Chronic Liver DiseasesOrphan nuclear receptors and the regulation of nutrient metabolism: understanding obesityEnergy metabolism in the liverCommonalities in the Association between PPARG and Vitamin D Related with Obesity and Carcinogenesis'Striking the Right Balance' in Targeting PPARgamma in the Metabolic Syndrome: Novel Insights from Human Genetic StudiesGlial cell line-derived neurotrophic factor protects against high-fat diet-induced hepatic steatosis by suppressing hepatic PPAR-γ expressionRegressive Effect of Myricetin on Hepatic Steatosis in Mice Fed a High-Fat DietSevere Atherosclerosis and Hypercholesterolemia in Mice Lacking Both the Melanocortin Type 4 Receptor and Low Density Lipoprotein ReceptorChanges in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob micePAS kinase is required for normal cellular energy balanceMolecular mediators of hepatic steatosis and liver injuryPPARs in obesity-induced T2DM, dyslipidaemia and NAFLD.PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers.Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPAR gamma hypomorphic mice.Effects of the PPARgamma agonist pioglitazone on lipoprotein metabolism in patients with type 2 diabetes mellitus.C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis.Immune and Metabolic Regulation Mechanism of Dangguiliuhuang Decoction against Insulin Resistance and Hepatic Steatosis.Prosteatotic genes are associated with unsaturated fat suppression of saturated fat-induced hepatic steatosis in C57BL/6 mice.Early hepatic insulin resistance precedes the onset of diabetes in obese C57BLKS-db/db mice.CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice.Hsp90 modulates PPARγ activity in a mouse model of nonalcoholic fatty liver disease.Sex dimorphic actions of rosiglitazone in generalised peroxisome proliferator-activated receptor-gamma (PPAR-gamma)-deficient micePPARs, Obesity, and InflammationInvolvement of inducible 6-phosphofructo-2-kinase in the anti-diabetic effect of peroxisome proliferator-activated receptor gamma activation in mice.Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harmGene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver.Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas.Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges.Supplementation of persimmon leaf ameliorates hyperglycemia, dyslipidemia and hepatic fat accumulation in type 2 diabetic mice.Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation.Emerging roles of the myocardin family of proteins in lipid and glucose metabolism.Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway.Protopanaxatriol, a novel PPARγ antagonist from Panax ginseng, alleviates steatosis in mice.
P2860
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P2860
Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Liver-specific disruption of P ...... ggravates diabetic phenotypes.
@ast
Liver-specific disruption of P ...... ggravates diabetic phenotypes.
@en
Liver-specific disruption of P ...... ggravates diabetic phenotypes.
@nl
type
label
Liver-specific disruption of P ...... ggravates diabetic phenotypes.
@ast
Liver-specific disruption of P ...... ggravates diabetic phenotypes.
@en
Liver-specific disruption of P ...... ggravates diabetic phenotypes.
@nl
prefLabel
Liver-specific disruption of P ...... ggravates diabetic phenotypes.
@ast
Liver-specific disruption of P ...... ggravates diabetic phenotypes.
@en
Liver-specific disruption of P ...... ggravates diabetic phenotypes.
@nl
P2093
P2860
P356
P1476
Liver-specific disruption of P ...... ggravates diabetic phenotypes.
@en
P2093
Bryan Brewer
Frank J Gonzalez
Gilles Lambert
Jerrold M Ward
Kimihiko Matsusue
Marc L Reitman
Martin Haluzik
Oksana Gavrilova
Sun-Hee Yim
P2860
P304
P356
10.1172/JCI200317223
P407
P577
2003-03-01T00:00:00Z