Bortezomib stabilizes mitotic cyclins and prevents cell cycle progression via inhibition of UBE2C in colorectal carcinoma. - Wikidata - wikimedia - TriplyDB

Bortezomib stabilizes mitotic cyclins and prevents cell cycle progression via inhibition of UBE2C in colorectal carcinoma.

Bortezomib stabilizes mitotic cyclins and prevents cell cycle progression via inhibition of UBE2C in colorectal carcinoma.

http://www.wikidata.org/entity/Q34839612

about

Targeting neuroblastoma stem cells with retinoic acid and proteasome inhibitor Temporal gene expression analysis of Sjögren's syndrome in C57BL/6.NOD-Aec1Aec2 mice based on microarray time-series data using an improved empirical Bayes approach.Ubiquitin-conjugating enzyme UBE2C is highly expressed in breast microcalcification lesions Leucovorin Enhances the Anti-cancer Effect of Bortezomib in Colorectal Cancer Cells.High expression of ubiquitin-conjugating enzyme 2C (UBE2C) correlates with nasopharyngeal carcinoma progression.UBE2C is a marker of unfavorable prognosis in bladder cancer after radical cystectomy.ALK gene amplification is associated with poor prognosis in colorectal carcinoma Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress.Mitotic catastrophe and cell cycle arrest are alternative cell death pathways executed by bortezomib in rituximab resistant B-cell lymphoma cells UBE2C induces EMT through Wnt/β‑catenin and PI3K/Akt signaling pathways by regulating phosphorylation levels of Aurora-A.New targeted approaches against the ubiquitin-proteasome system in gastrointestinal malignancies.Therapeutic targeting of cancer cell cycle using proteasome inhibitors β-Arrestin 1 has an essential role in neurokinin-1 receptor-mediated glioblastoma cell proliferation and G2/M phase transition.High expression of UBE2C is associated with the aggressive progression and poor outcome of malignant glioma.Ubiquitin-conjugating enzyme E2C regulates apoptosis-dependent tumor progression of non-small cell lung cancer via ERK pathway.A dock derived compound against laminin receptor (37 LR) exhibits anti-cancer properties in a prostate cancer cell line model.Ten hub genes associated with progression and prognosis of pancreatic carcinoma identified by co-expression analysis.Identification of Candidate Biomarkers Correlated With the Pathogenesis and Prognosis of Non-small Cell Lung Cancer via Integrated Bioinformatics Analysis

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Bortezomib stabilizes mitotic cyclins and prevents cell cycle progression via inhibition of UBE2C in colorectal carcinoma.

http://www.wikidata.org/entity/Q34839612

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Bortezomib stabilizes mitotic ...... UBE2C in colorectal carcinoma.

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Bortezomib stabilizes mitotic ...... UBE2C in colorectal carcinoma.

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Bortezomib stabilizes mitotic ...... UBE2C in colorectal carcinoma.

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type

label

Bortezomib stabilizes mitotic ...... UBE2C in colorectal carcinoma.

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Bortezomib stabilizes mitotic ...... UBE2C in colorectal carcinoma.

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Bortezomib stabilizes mitotic ...... UBE2C in colorectal carcinoma.

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Bortezomib stabilizes mitotic ...... UBE2C in colorectal carcinoma.

@ast

Bortezomib stabilizes mitotic ...... UBE2C in colorectal carcinoma.

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Bortezomib stabilizes mitotic ...... UBE2C in colorectal carcinoma.

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J.AJPATH.2011.01.034

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The American Journal of Pathology

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Bortezomib stabilizes mitotic ...... UBE2C in colorectal carcinoma.

@en

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Alaa Abduljabbar

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Azhar R Hussain

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Fouad Al-Dayel

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Jehad Abubaker

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Khawla S Al-Kuraya

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Luai H Ashari

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Maqbool Ahmed

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Mehar Sultana

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Nasser Al-Sanea

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Prashant Bavi

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P2860

Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase

UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas

Expression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinoma

Themes and variations on ubiquitylation

Cell cycle regulation by the ubiquitin pathway

The ubiquitin-proteasome system

Identification of overexpressed genes in hepatocellular carcinoma, with special reference to ubiquitin-conjugating enzyme E2C gene expression.

Bortezomib with or without irinotecan in relapsed or refractory colorectal cancer: results from a randomized phase II study.

Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer.

UbcH10 is the cancer-related E2 ubiquitin-conjugating enzyme.

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2109-2120

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10.1016/J.AJPATH.2011.01.034

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2011-05-01T00:00:00Z

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