NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability
about
SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysExposure to heavy ion radiation induces persistent oxidative stress in mouse intestineNADPH Oxidase Activation Contributes to Heavy Ion Irradiation-Induced Cell Death.The efficacy of human placenta-derived mesenchymal stem cells on radiation enteropathy along with proteomic biomarkers predicting a favorable response.Effects of ionizing radiation on biological molecules--mechanisms of damage and emerging methods of detectionRadiation hormesis: Autophagy and other cellular mechanisms.Rational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents.The mechanisms of radiation-induced bystander effectDiverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimicsInactivation of NADPH oxidases NOX4 and NOX5 protects human primary fibroblasts from ionizing radiation-induced DNA damage.Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel.Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumorsReactive oxygen species and hematopoietic stem cell senescence.Redox control of leukemia: from molecular mechanisms to therapeutic opportunities.Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts.Whole-body proton irradiation causes long-term damage to hematopoietic stem cells in mice.Adaptive and Pathogenic Responses to Stress by Stem Cells during Development.Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury.Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+).Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.Intraclonal recovery of 'slow clones'-a manifestation of genomic instability: are mitochondria the key to an explanation?Ionizing radiation-induced oxidative stress, epigenetic changes and genomic instability: the pivotal role of mitochondria.NADPH oxidase-generated hydrogen peroxide induces DNA damage in mutant FLT3-expressing leukemia cells.Optimal ROS Signaling Is Critical for Nuclear Reprogramming.Reduction-oxidation (redox) system in radiation-induced normal tissue injury: molecular mechanisms and implications in radiation therapeutics.Radiation-mediated tumor growth inhibition is significantly enhanced with redox-active compounds that cycle with ascorbate.
P2860
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P2860
NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
NADPH oxidase inhibition atten ...... atopoietic genomic instability
@ast
NADPH oxidase inhibition atten ...... atopoietic genomic instability
@en
NADPH oxidase inhibition atten ...... atopoietic genomic instability
@nl
type
label
NADPH oxidase inhibition atten ...... atopoietic genomic instability
@ast
NADPH oxidase inhibition atten ...... atopoietic genomic instability
@en
NADPH oxidase inhibition atten ...... atopoietic genomic instability
@nl
prefLabel
NADPH oxidase inhibition atten ...... atopoietic genomic instability
@ast
NADPH oxidase inhibition atten ...... atopoietic genomic instability
@en
NADPH oxidase inhibition atten ...... atopoietic genomic instability
@nl
P2093
P2860
P356
P1433
P1476
NADPH oxidase inhibition atten ...... atopoietic genomic instability
@en
P2093
Daohong Zhou
Hongliang Li
Ines Batinic-Haberle
Senthil K Pazhanisamy
P2860
P304
P356
10.1093/MUTAGE/GER001
P577
2011-03-17T00:00:00Z