Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells - Wikidata - wikimedia - TriplyDB

Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells

Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells

http://www.wikidata.org/entity/Q34856800

about

Immune checkpoint inhibitors: the new frontier in non-small-cell lung cancer treatment Lymphocyte-activation gene-3, an important immune checkpoint in cancer Fueling the engine and releasing the break: combinational therapy of cancer vaccines and immune checkpoint inhibitors Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators Molecular and cellular insights into T cell exhaustion From tumor immunosuppression to eradication: targeting homing and activity of immune effector cells to tumors CTLA-4 blockade in tumor models: an overview of preclinical and translational research The blockade of immune checkpoints in cancer immunotherapy Combination Approaches with Immune-Checkpoint Blockade in Cancer Therapy Immune checkpoint blockade: a common denominator approach to cancer therapy High avidity cytotoxic T lymphocytes can be selected into the memory pool but they are exquisitely sensitive to functional impairment Checkpoint inhibitors in hematological malignancies Lymphocyte activation gene 3: a novel therapeutic target in chronic lymphocytic leukemia.Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape Lymphocyte activation gene-3 expression defines a discrete subset of HIV-specific CD8+ T cells that is associated with lower viral load Targeting CD8+ T-cell tolerance for cancer immunotherapy.PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice Induction and function of virus-specific CD4+ T cell responses.Differential Regulation of the Immune Response in the Spleen and Liver of Mice Infected with Leishmania donovani.Anti-tumor effects of endogenous prostate cancer-specific CD8 T cells in a murine TCR transgenic model Upregulation of Immune Checkpoint Molecules, PD-1 and LAG-3, on CD4+ and CD8+ T Cells after Gastric Cancer Surgery.Elevated tumor-associated antigen expression suppresses variant peptide vaccine responses.Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice.CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.LAG-3 in Cancer Immunotherapy.Blockade of Programmed Death 1 Augments the Ability of Human T Cells Engineered to Target NY-ESO-1 to Control Tumor Growth after Adoptive Transfer.Expression of inhibitory receptors on intratumoral T cells modulates the activity of a T cell-bispecific antibody targeting folate receptor.Activated T cells sustain myeloid-derived suppressor cell-mediated immune suppression.Personalized Oncology Meets Immunology: The Path toward Precision Immunotherapy.Increasing LAG-3 expression suppresses T-cell function in chronic hepatitis B: A balance between immunity strength and liver injury extent.Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8+ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors.Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy The CD4-like molecule LAG-3, biology and therapeutic applications.Apoptosis - an Ubiquitous T cell Immunomodulator.Immune evasion in acute myeloid leukemia: current concepts and future directions.Armed therapeutic viruses - a disruptive therapy on the horizon of cancer immunotherapy.OX40 Agonists and Combination Immunotherapy: Putting the Pedal to the Metal.Immunomodulatory Drugs: Immune Checkpoint Agents in Acute Leukemia.Virus-specific T-cell therapy in solid organ transplantation.Cancer and the Immune System: Basic Concepts and Targets for Intervention.

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P2860

Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells

http://www.wikidata.org/entity/Q34856800

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Functionally distinct LAG-3 an ...... nically stimulated CD8 T cells

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Functionally distinct LAG-3 an ...... nically stimulated CD8 T cells

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Functionally distinct LAG-3 an ...... nically stimulated CD8 T cells

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Functionally distinct LAG-3 an ...... nically stimulated CD8 T cells

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Functionally distinct LAG-3 an ...... nically stimulated CD8 T cells

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Functionally distinct LAG-3 an ...... nically stimulated CD8 T cells

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JIMMUNOL.0804211

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Journal of Immunology

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Functionally distinct LAG-3 an ...... nically stimulated CD8 T cells

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Charles G Drake

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Dario A A Vignali

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Derese Getnet

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Drew M Pardoll

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Edward Hipkiss

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Hung-Rong Yen

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Joseph F Grosso

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Kristin J Pyle

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Monica V Goldberg

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Tullia C Bruno

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P2860

LAG-3, a novel lymphocyte activation gene closely related to CD4

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

Lineage relationship and protective immunity of memory CD8 T cell subsets

Restoring function in exhausted CD8 T cells during chronic viral infection

Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors

Regulatory T cells and immune tolerance

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen.

Self-antigen prevents CD8 T cell effector differentiation by CD134 and CD137 dual costimulation.

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6659-6669

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10.4049/JIMMUNOL.0804211

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11

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182

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2009-06-01T00:00:00Z

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24439325

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19454660

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3082361

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