Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis
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Deficiency for the cysteine protease cathepsin L impairs Myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancerValidation of the Cancer BioChip System as a 3D siRNA screening tool for breast cancer targetsPericellular proteolysis in cancerB-cell lymphopoiesis is regulated by cathepsin L.Lysosomal protein turnover contributes to the acquisition of TGFβ-1 induced invasive properties of mammary cancer cells.Protective role of cathepsin L in mouse skin carcinogenesis.Epigenetic regulation of cathepsin L expression in chronic myeloid leukaemiaCysteine cathepsins S and L modulate anti-angiogenic activities of human endostatin.Live-cell imaging of tumor proteolysis: impact of cellular and non-cellular microenvironmentThe role of the PI3K/Akt/mTOR signalling pathway in human cancers induced by infection with human papillomaviruses.Human cathepsin V protease participates in production of enkephalin and NPY neuropeptide neurotransmitters.Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target.Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancerThree-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins.Proteolytic networks in cancerCathepsin C is a tissue-specific regulator of squamous carcinogenesis.Cathepsin L in metastatic bone disease: therapeutic implications.Cathepsin L in tumor angiogenesis and its therapeutic intervention by the small molecule inhibitor KGP94.Specialized roles for cysteine cathepsins in health and disease.Cancer-associated lysosomal changes: friends or foes?Cysteine proteases: mode of action and role in epidermal differentiation.Cathepsin B: multiple roles in cancer.Formalin-Fixed, Paraffin-Embedded Tissues (FFPE) as a Robust Source for the Profiling of Native and Protease-Generated Protein Amino Termini.Inherited diseases caused by mutations in cathepsin protease genes.Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts.Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo.Impaired turnover of autophagolysosomes in cathepsin L deficiency.Cystatin C deficiency suppresses tumor growth in a breast cancer model through decreased proliferation of tumor cells.Clinical features of cystatin A expression in patients with pancreatic ductal adenocarcinoma.MicroRNA-152 inhibits tumor cell growth while inducing apoptosis via the transcriptional repression of cathepsin L in gastrointestinal stromal tumor.Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes.Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice
P2860
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P2860
Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Deficiency for the cysteine pr ...... progression in mouse epidermis
@ast
Deficiency for the cysteine pr ...... progression in mouse epidermis
@en
Deficiency for the cysteine pr ...... progression in mouse epidermis
@nl
type
label
Deficiency for the cysteine pr ...... progression in mouse epidermis
@ast
Deficiency for the cysteine pr ...... progression in mouse epidermis
@en
Deficiency for the cysteine pr ...... progression in mouse epidermis
@nl
prefLabel
Deficiency for the cysteine pr ...... progression in mouse epidermis
@ast
Deficiency for the cysteine pr ...... progression in mouse epidermis
@en
Deficiency for the cysteine pr ...... progression in mouse epidermis
@nl
P2093
P2860
P356
P1433
P1476
Deficiency for the cysteine pr ...... progression in mouse epidermis
@en
P2093
J Dennemärker
L M Coussens
T Lohmüller
T Reinheckel
P2860
P2888
P304
P356
10.1038/ONC.2009.466
P407
P577
2009-12-21T00:00:00Z
P5875
P6179
1052437331