Biology of platelet-activating factor acetylhydrolase (PAF-AH, lipoprotein associated phospholipase A2).
about
To hydrolyze or not to hydrolyze: the dilemma of platelet-activating factor acetylhydrolasePhospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionCirculating biologically active oxidized phospholipids show on-going and increased oxidative stress in older male mice.The platelet activating factor (PAF) signaling cascade in systemic inflammatory responsesPhospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsLipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipidsBiosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicityEffect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: a randomized, controlled trialGenome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.The inhibition of lipoprotein-associated phospholipase A2 exerts beneficial effects against atherosclerosis in LDLR-deficient mice.Studies on HDL associated enzymes under experimental hypercholesterolemia: possible modulation on selenium supplementation.PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cellsCerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity is increased in Alzheimer disease.Chronic alcohol exposure increases circulating bioactive oxidized phospholipids.Inhibition of lipoprotein-associated phospholipase A2 ameliorates inflammation and decreases atherosclerotic plaque formation in ApoE-deficient mice.Lysophosphatidic acid in atherosclerotic diseasesCirculating platelet-activating factor is primarily cleared by transport, not intravascular hydrolysis by lipoprotein-associated phospholipase A2/ PAF acetylhydrolaseHuman TMEM30a promotes uptake of antitumor and bioactive choline phospholipids into mammalian cellsThe emerging roles of PAF acetylhydrolase.Mouse plasminogen has oxidized phosphatidylcholine adducts that are not metabolized by lipoprotein-associated phospholipase A₂under basal conditionsIntracellular erythrocyte platelet-activating factor acetylhydrolase I inactivates aspirin in blood.Fish polar lipids retard atherosclerosis in rabbits by down-regulating PAF biosynthesis and up-regulating PAF catabolismPlatelet-activating factor stimulates sodium-hydrogen exchange in ventricular myocytes.cDNA cloning and expression pattern of homolog of alpha subunit of platelet-activating factor acetylhydrolase Ib from the Chinese oak silkworm, Antheraea pernyi.Cytosolic phospholipase A₂: physiological function and role in disease.Lung endothelial cell platelet-activating factor production and inflammatory cell adherence are increased in response to cigarette smoke component exposure.Modulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A2Lipoprotein-associated phospholipase A(2) and future risk of subclinical disease and cardiovascular events in individuals with type 2 diabetes: the Cardiovascular Health Study.Platelet activating factor levels and metabolism in Tangier disease: a case study.Acute impact of apheresis on oxidized phospholipids in patients with familial hypercholesterolemiaHypoxia-mediated impaired erythrocyte Lands' Cycle is pathogenic for sickle cell disease.HDL is the major lipoprotein carrier of plasma F2-isoprostanes.Radiation therapy generates platelet-activating factor agonistsIntracellular- and extracellular-derived Ca(2+) influence phospholipase A(2)-mediated fatty acid release from brain phospholipids.A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults.Suppression of mitochondrial function by oxidatively truncated phospholipids is reversible, aided by bid, and suppressed by Bcl-XLInvestigation of the Brain Biodistribution of the Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitor [18F]GSK2647544 in Healthy Male Subjects.Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases.Low acylation stimulating protein levels are associated with cardiometabolic disorders-secondary to autoimmune activation?Lipoprotein-associated phospholipase A₂ mass level is increased in elderly subjects with type 2 diabetes mellitus.
P2860
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P2860
Biology of platelet-activating factor acetylhydrolase (PAF-AH, lipoprotein associated phospholipase A2).
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Biology of platelet-activating ...... associated phospholipase A2).
@ast
Biology of platelet-activating ...... associated phospholipase A2).
@en
Biology of platelet-activating ...... associated phospholipase A2).
@nl
type
label
Biology of platelet-activating ...... associated phospholipase A2).
@ast
Biology of platelet-activating ...... associated phospholipase A2).
@en
Biology of platelet-activating ...... associated phospholipase A2).
@nl
prefLabel
Biology of platelet-activating ...... associated phospholipase A2).
@ast
Biology of platelet-activating ...... associated phospholipase A2).
@en
Biology of platelet-activating ...... associated phospholipase A2).
@nl
P2860
P1476
Biology of platelet-activating ...... associated phospholipase A2).
@en
P2093
Diana M Stafforini
P2860
P356
10.1007/S10557-008-6133-8
P577
2008-10-24T00:00:00Z