Lowering glycosphingolipid levels in CD4+ T cells attenuates T cell receptor signaling, cytokine production, and differentiation to the Th17 lineage.
about
Diversity of IL-17-producing T lymphocytesn-3 PUFAs reduce T-helper 17 cell differentiation by decreasing responsiveness to interleukin-6 in isolated mouse splenic CD4⁺ T cells.Ganglioside GM3 has an essential role in the pathogenesis and progression of rheumatoid arthritis.Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunctionReducing FLI1 levels in the MRL/lpr lupus mouse model impacts T cell function by modulating glycosphingolipid metabolismTh17 cell accumulation is decreased during chronic experimental colitis by (n-3) PUFA in Fat-1 mice.CD4 and CD8 T cells require different membrane gangliosides for activation.Role of glycosphingolipids in dendritic cell-mediated HIV-1 trans-infection.Normalizing glycosphingolipids restores function in CD4+ T cells from lupus patients.Heterogeneity of gangliosides among T cell subsets.Omega-3 fatty acids, lipid rafts, and T cell signalingLipid rafts in immune signalling: current progress and future perspective.Regulation of T cell signalling by membrane lipids.Activation of human naïve Th cells increases surface expression of GD3 and induces neoexpression of GD2 that colocalize with TCR clusters.Transcriptional Regulation of T-Cell Lipid Metabolism: Implications for Plasma Membrane Lipid Rafts and T-Cell Function.
P2860
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P2860
Lowering glycosphingolipid levels in CD4+ T cells attenuates T cell receptor signaling, cytokine production, and differentiation to the Th17 lineage.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Lowering glycosphingolipid lev ...... entiation to the Th17 lineage.
@ast
Lowering glycosphingolipid lev ...... entiation to the Th17 lineage.
@en
Lowering glycosphingolipid lev ...... entiation to the Th17 lineage.
@nl
type
label
Lowering glycosphingolipid lev ...... entiation to the Th17 lineage.
@ast
Lowering glycosphingolipid lev ...... entiation to the Th17 lineage.
@en
Lowering glycosphingolipid lev ...... entiation to the Th17 lineage.
@nl
prefLabel
Lowering glycosphingolipid lev ...... entiation to the Th17 lineage.
@ast
Lowering glycosphingolipid lev ...... entiation to the Th17 lineage.
@en
Lowering glycosphingolipid lev ...... entiation to the Th17 lineage.
@nl
P2093
P2860
P356
P1476
Lowering glycosphingolipid lev ...... entiation to the Th17 lineage.
@en
P2093
Andrea Edling
Canwen Jiang
Craig Siegel
Hongmei Zhao
James A Shayman
Ji-Lei Jiang
Jinhua Zhang
Johanne Kaplan
Jozsef Karman
Nathan Gumlaw
P2860
P304
14787-14794
P356
10.1074/JBC.M111.218610
P407
P577
2011-03-14T00:00:00Z