Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
about
Functional Diversification of Motor Neuron-specific Isl1 Enhancers during EvolutionTranscription factor regulation of pancreatic organogenesis, differentiation and maturationArx is required for normal enteroendocrine cell development in mice and humansA genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tractLIM-homeodomain transcription factor Isl-1 mediates kisspeptin's effect on insulin secretion in mice.Expression of Isl1 during mouse developmentIslet-1 Is essential for pancreatic β-cell function.Impaired enteroendocrine development in intestinal-specific Islet1 mouse mutants causes impaired glucose homeostasis.Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic β-Cell Target Genes.Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice.Transgenic studies on homeobox genes in nervous system development: spina bifida in Isl1 transgenic miceSingle-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Gene regulatory networks governing pancreas development.Elevation of transcription factor Islet-1 levels in vivo increases β-cell function but not β-cell massIntegration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes.Cell type and tissue specific function of islet genes in zebrafish pancreas development.Alpha TC1 and Beta-TC-6 genomic profiling uncovers both shared and distinct transcriptional regulatory features with their primary islet counterparts.Development and regeneration in the endocrine pancreas
P2860
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P2860
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
@ast
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
@en
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
@nl
type
label
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
@ast
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
@en
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
@nl
prefLabel
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
@ast
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
@en
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
@nl
P2093
P2860
P356
P1476
Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development
@en
P2093
Benjamin Ediger
Catherine Lee May
Jingxuan Liu
Johanna Murray
Roland Stein
P2860
P304
15352-15360
P356
10.1074/JBC.M111.231670
P407
P577
2011-03-09T00:00:00Z