Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin. - Wikidata - wikimedia - TriplyDB

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

http://www.wikidata.org/entity/Q34870969

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Plakoglobin: role in tumorigenesis and metastasis The desmosome Desmosomes in acquired disease Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgaris Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism Transcriptional and functional differences in stem cell populations isolated from extraocular and limb muscles.Pemphigus vulgaris IgG cause loss of desmoglein-mediated adhesion and keratinocyte dissociation independent of epidermal growth factor receptor Peptides Targeting the Desmoglein 3 Adhesive Interface Prevent Autoantibody-induced Acantholysis in Pemphigus.Pathogenic epitopes of autoantibodies in pemphigus reside in the amino-terminal adhesive region of desmogleins which are unmasked by proteolytic processing of prosequence.p38MAPK signaling and desmoglein-3 internalization are linked events in pemphigus acantholysis.Mechanisms of Autoantibody-Induced Pathology.Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src Mouse models for blistering skin disorders.Superficial dsg2 expression limits epidermal blister formation mediated by pemphigus foliaceus antibodies and exfoliative toxins.The biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium.Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.Signaling dependent and independent mechanisms in pemphigus vulgaris blister formation Desmoglein as a target in skin disease and beyond.DSG3 facilitates cancer cell growth and invasion through the DSG3-plakoglobin-TCF/LEF-Myc/cyclin D1/MMP signaling pathway Plakoglobin represses SATB1 expression and decreases in vitro proliferation, migration and invasion.Structure, function, and regulation of desmosomes.Nuclear signaling from cadherin adhesion complexes Desmoglein-2: a novel regulator of apoptosis in the intestinal epithelium.Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability.Beyond cell adhesion: the role of armadillo proteins in the heart Peptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blistering Pemphigus in the XXI century: new life to an old story.The desmosome and pemphigus.A pathophysiologic role for epidermal growth factor receptor in pemphigus acantholysis Plakoglobin Reduces the in vitro Growth, Migration and Invasion of Ovarian Cancer Cells Expressing N-Cadherin and Mutant p53.Desmosomes: just cell adhesion or is there more?MYC in mammalian epidermis: how can an oncogene stimulate differentiation?Plakoglobin as a regulator of desmocollin gene expression.Desmosomes: new perpetrators in tumour suppression Advances in pemphigus and its endemic pemphigus foliaceus (Fogo Selvagem) phenotype: a paradigm of human autoimmunity.Desmoglein 1-dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis Involvement of the apoptotic mechanism in pemphigus foliaceus autoimmune injury of the skin.Disruption of desmosome assembly by monovalent human pemphigus vulgaris monoclonal antibodies.Pemphigus: the promises of peptide immunotherapy.

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P2860

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

http://www.wikidata.org/entity/Q34870969

description

2006 nî lūn-bûn

@nan

2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2006 թվականի հուլիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

@ast

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

@en

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

@nl

type

label

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

@ast

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

@en

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

@nl

prefLabel

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

@ast

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

@en

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

@nl

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SJ.EMBOJ.7601224

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The EMBO Journal

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Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

@en

P2093

Alain de Bruin

http://www.w3.org/2001/XMLSchema#string

Anthony Zakher

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Eliane J Müller

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Horst Posthaus

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Lina Williamson

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Maja M Suter

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Natalia A Raess

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Reinhard Bolli

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Reto Caldelari

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Thomas Hunziker

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P2860

Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin

The human plakoglobin gene localizes on chromosome 17q21 and is subjected to loss of heterozygosity in breast and ovarian cancers

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

Axin directly interacts with plakoglobin and regulates its stability

Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents

Lack of mucosal involvement in pemphigus foliaceus may be due to low expression of desmoglein 1

LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

beta-catenin is a target for the ubiquitin-proteasome pathway

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