Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
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KIFC1: a promising chemotherapy target for cancer treatment?Recent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapyTranslating Proteomic Into Functional Data: An High Mobility Group A1 (HMGA1) Proteomic Signature Has Prognostic Value in Breast CancerDiscovery of a novel inhibitor of kinesin-like protein KIFC1KIFCI, a novel putative prognostic biomarker for ovarian adenocarcinomas: delineating protein interaction networks and signaling circuitries.Causes and consequences of centrosome abnormalities in cancer.HSET overexpression fuels tumor progression via centrosome clustering-independent mechanisms in breast cancer patientsThe Aspergillus nidulans bimC4 mutation provides an excellent tool for identification of kinesin-14 inhibitors.Extensive Transcriptomic and Genomic Analysis Provides New Insights about Luminal Breast Cancers.KIFC1 is a novel potential therapeutic target for breast cancer.Multi-institutional study of nuclear KIFC1 as a biomarker of poor prognosis in African American women with triple-negative breast cancerAmplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cellsMitotic spindle multipolarity without centrosome amplification.Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues.Discovery of Novel Allosteric Eg5 Inhibitors Through Structure-Based Virtual Screening.Site-selective Suzuki-Miyaura coupling of heteroaryl halides - understanding the trends for pharmaceutically important classes.Motoring through: the role of kinesin superfamily proteins in female meiosis.Quantitative multi-parametric evaluation of centrosome declustering drugs: centrosome amplification, mitotic phenotype, cell cycle and deathDividing with Extra Centrosomes: A Double Edged Sword for Cancer Cells.C-terminal kinesin motor KIFC1 participates in facilitating proper cell division of human seminomaStructural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.Structural basis of human kinesin-8 function and inhibition.Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells.Kinesin superfamily: roles in breast cancer, patient prognosis and therapeutics.Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment.Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer.Using Cell Culture Models of Centrosome Amplification to Study Centrosome Clustering in Cancer.
P2860
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P2860
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
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2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
@ast
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
@en
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
@nl
type
label
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
@ast
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
@en
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
@nl
prefLabel
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
@ast
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
@en
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
@nl
P2093
P356
P1433
P1476
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
@en
P2093
Claudio Chuaqui
Farzin Gharahdaghi
Huawei Chen
Jiaquan Wu
Keith Mikule
Kelly Jacques
Michelle L Lamb
P304
P356
10.1021/CB400186W
P577
2013-08-16T00:00:00Z