Constitutively active AR-V7 plays an essential role in the development and progression of castration-resistant prostate cancer.
about
Splice Variants of Androgen Receptor and Prostate CancerNovel Insights into Molecular Indicators of Response and Resistance to Modern Androgen-Axis Therapies in Prostate CancerEmerging data on androgen receptor splice variants in prostate cancerDiagnosis of adults Xp11.2 translocation renal cell carcinoma by immunohistochemistry and FISH assays: clinicopathological data from ethnic Chinese populationPiecing the puzzle together: Docetaxel cycles and current considerations in the treatment of metastatic castration-resistant prostate cancer.Triptolide Inhibits the AR Signaling Pathway to Suppress the Proliferation of Enzalutamide Resistant Prostate Cancer Cells.Enzalutamide: a review of its use in chemotherapy-naïve metastatic castration-resistant prostate cancer.Identification of Androgen Receptor Splice Variants in the Pten Deficient Murine Prostate Cancer Model.High-Content Screening Identifies Src Family Kinases as Potential Regulators of AR-V7 Expression and Androgen-Independent Cell Growth.RNA biomarkers to facilitate the identification of aggressive prostate cancerPROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer.Droplet Digital PCR Based Androgen Receptor Variant 7 (AR-V7) Detection from Prostate Cancer Patient Blood BiopsiesFunctional variants of the 5-methyltetrahydrofolate-homocysteine methyltransferase gene significantly increase susceptibility to prostate cancer: Results from an ethnic Han Chinese populationMTHFR c.677C>T Inhibits Cell Proliferation and Decreases Prostate Cancer Susceptibility in the Han Chinese Population in Shanghai.Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate Cancer.Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells.Moving Beyond the Androgen Receptor (AR): Targeting AR-Interacting Proteins to Treat Prostate Cancer.AR-v7 protein expression is regulated by protein kinase and phosphatase.Heat shock protein 70 inhibitors suppress androgen receptor expression in LNCaP95 prostate cancer cells.A novel capillary nano-immunoassay for assessing androgen receptor splice variant 7 in plasma. Correlation with CD133 antigen expression in circulating tumor cells. A pilot study in prostate cancer patients.Interplay between Cytoplasmic and Nuclear Androgen Receptor Splice Variants Mediates Castration Resistance.Progress in the mechanism and drug development of castration-resistant prostate cancer.Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting.Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408)] or mTOR [rapamycin] inhibition in prostate cancer cell models.Androgen receptor variation affects prostate cancer progression and drug resistance.Genomic tests to guide prostate cancer management following diagnosis.Androgen Receptor Rearrangement and Splicing Variants in Resistance to Endocrine Therapies in Prostate Cancer.Dissecting the roles of the androgen receptor in prostate cancer from molecular perspectives.Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases.Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer.Clinical Relevance of Androgen Receptor Splice Variants in Castration-Resistant Prostate Cancer.Nuclear-specific AR-V7 Protein Localization is Necessary to Guide Treatment Selection in Metastatic Castration-resistant Prostate Cancer.Snail promotes resistance to enzalutamide through regulation of androgen receptor activity in prostate cancer.Low TIM3 expression indicates poor prognosis of metastatic prostate cancer and acts as an independent predictor of castration resistant status.Resveratrol enhances polyubiquitination-mediated ARV7 degradation in prostate cancer cells.A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate CancerClinical relevance of androgen receptor alterations in prostate cancer.Androgen Receptor Variant AR-V9 Is Coexpressed with AR-V7 in Prostate Cancer Metastases and Predicts Abiraterone Resistance.Androgen-receptor splice variant-7-positive prostate cancer: a novel molecular subtype with markedly worse androgen-deprivation therapy outcomes in newly diagnosed patients.Cost-Savings Analysis of AR-V7 Testing in Patients With Metastatic Castration-Resistant Prostate Cancer Eligible for Treatment With Abiraterone or Enzalutamide.
P2860
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P2860
Constitutively active AR-V7 plays an essential role in the development and progression of castration-resistant prostate cancer.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Constitutively active AR-V7 pl ...... ion-resistant prostate cancer.
@ast
Constitutively active AR-V7 pl ...... ion-resistant prostate cancer.
@en
Constitutively active AR-V7 pl ...... ion-resistant prostate cancer.
@nl
type
label
Constitutively active AR-V7 pl ...... ion-resistant prostate cancer.
@ast
Constitutively active AR-V7 pl ...... ion-resistant prostate cancer.
@en
Constitutively active AR-V7 pl ...... ion-resistant prostate cancer.
@nl
prefLabel
Constitutively active AR-V7 pl ...... ion-resistant prostate cancer.
@ast
Constitutively active AR-V7 pl ...... ion-resistant prostate cancer.
@en
Constitutively active AR-V7 pl ...... ion-resistant prostate cancer.
@nl
P2093
P2860
P356
P1433
P1476
Constitutively active AR-V7 pl ...... ion-resistant prostate cancer.
@en
P2093
Dingwei Ye
Guohai Shi
Hailiang Zhang
Xiaoqun Yang
Yuanyuan Qu
Yunyi Kong
Zhongwei Jia
P2860
P2888
P356
10.1038/SREP07654
P407
P50
P577
2015-01-07T00:00:00Z
P5875
P6179
1014573018