Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion - Wikidata - wikimedia - TriplyDB

Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion

Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion

http://www.wikidata.org/entity/Q34888337

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Red blood cell invasion by Plasmodium vivax: structural basis for DBP engagement of DARC Applications of (19)F-NMR in Fragment-Based Drug Discovery Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial for Plasmodium falciparum erythrocyte invasion Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion.Molecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism Plasmodium falciparum aldolase and the C-terminal cytoplasmic domain of certain apical organellar proteins promote actin polymerization AlphaScreen-Based Assays: Ultra-High-Throughput Screening for Small-Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum.Immunization with the Malaria Diversity-Covering Blood-Stage Vaccine Candidate Plasmodium falciparum Apical Membrane Antigen 1 DiCo in Complex with Its Natural Ligand PfRon2 Does Not Improve the In Vitro Efficacy.Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria.Cheminformatics Based Machine Learning Models for AMA1-RON2 Abrogators for Inhibiting Plasmodium falciparum Erythrocyte Invasion.Computational prediction of protein interactions related to the invasion of erythrocytes by malarial parasites Host cell invasion by apicomplexan parasites: the junction conundrum The shear stress of host cell invasion: exploring the role of biomolecular complexes Computational and biophysical approaches to protein-protein interaction inhibition of Plasmodium falciparum AMA1/RON2 complex.An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity Expression, Purification, and Biological Characterization of Babesia microti Apical Membrane Antigen 1.Stability of the Plasmodium falciparum AMA1-RON2 Complex Is Governed by the Domain II (DII) Loop Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair Targets and Mechanisms Associated with Protection from Severe Plasmodium falciparum Malaria in Kenyan Children.Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium A Toxoplasma gondii Ortholog of Plasmodium GAMA Contributes to Parasite Attachment and Cell Invasion.Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi From crystal to compound: structure-based antimalarial drug discovery.The apicomplexan glideosome and adhesins - Structures and function.A malaria vaccine protects Aotus monkeys against virulent Plasmodium falciparum infection Heparin: new life for an old drug.Plasticity and redundancy among AMA-RON pairs ensure host cell entry of Toxoplasma parasites.Bioinformatic Identification of Peptidomimetic-Based Inhibitors against Plasmodium falciparum Antigen AMA1.Anticancer Properties of Halogenated Pyrrolo[3,2-d]pyrimidines with Decreased Toxicity via N5 Substitution.Basigin Interacts with Plasmodium vivax Tryptophan-rich Antigen PvTRAg38 as a Second Erythrocyte Receptor to Promote Parasite Growth.Self-assembling functional programmable protein array for studying protein-protein interactions in malaria parasites Antimalarial drug discovery targeting apical membrane antigen 1 A critical evaluation of pyrrolo[2,3-d]pyrimidine-4-amines as Plasmodium falciparum apical membrane antigen 1 (AMA1) inhibitors Babesia bovis RON2 contains conserved B-cell epitopes that induce an invasion-blocking humoral immune response in immunized cattle

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P2860

Disrupting malaria parasite AMA1-RON2 interaction with a small molecule prevents erythrocyte invasion

http://www.wikidata.org/entity/Q34888337

description

2013 nî lūn-bûn

@nan

2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Disrupting malaria parasite AM ...... prevents erythrocyte invasion

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Disrupting malaria parasite AM ...... prevents erythrocyte invasion

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Disrupting malaria parasite AM ...... prevents erythrocyte invasion

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type

label

Disrupting malaria parasite AM ...... prevents erythrocyte invasion

@ast

Disrupting malaria parasite AM ...... prevents erythrocyte invasion

@en

Disrupting malaria parasite AM ...... prevents erythrocyte invasion

@nl

prefLabel

Disrupting malaria parasite AM ...... prevents erythrocyte invasion

@ast

Disrupting malaria parasite AM ...... prevents erythrocyte invasion

@en

Disrupting malaria parasite AM ...... prevents erythrocyte invasion

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Nature Communications

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Disrupting malaria parasite AM ...... prevents erythrocyte invasion

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David J Maloney

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Diane K Luci

http://www.w3.org/2001/XMLSchema#string

Hongmao Sun

http://www.w3.org/2001/XMLSchema#string

J David Haynes

http://www.w3.org/2001/XMLSchema#string

J Kathleen Moch

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John Andersen

http://www.w3.org/2001/XMLSchema#string

Prakash Srinivasan

http://www.w3.org/2001/XMLSchema#string

Wandy L Beatty

http://www.w3.org/2001/XMLSchema#string

Xin Hu

http://www.w3.org/2001/XMLSchema#string

P2860

Global malaria mortality between 1980 and 2010: a systematic analysis

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

Small-molecule inhibitors of dengue-virus entry

Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote

Distinct external signals trigger sequential release of apical organelles during erythrocyte invasion by malaria parasites

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

Host cell invasion by apicomplexan parasites: insights from the co-structure of AMA1 with a RON2 peptide

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2261

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scholarly article

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10.1038/NCOMMS3261

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P478

4

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Louis H. Miller

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2013-01-01T00:00:00Z

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254266408

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1024177574

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23907321

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malaria prevention

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3755449

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