Multivalent smallpox DNA vaccine delivered by intradermal electroporation drives protective immunity in nonhuman primates against lethal monkeypox challenge.
about
Side-by-side comparison of gene-based smallpox vaccine with MVA in nonhuman primatesImmunogenicity of DNA vaccines encoding simian immunodeficiency virus antigen targeted to dendritic cells in rhesus macaquesProtective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine.Fusion of antigen to a dendritic cell targeting chemokine combined with adjuvant yields a malaria DNA vaccine with enhanced protective capabilitiesOptimization of electroporation-enhanced intradermal delivery of DNA vaccine using a minimally invasive surface device.A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skinProtective antigens against glanders identified by expression library immunization.Electro-gene transfer to skin using a noninvasive multielectrode array.HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivoComparison of plasmid vaccine immunization schedules using intradermal in vivo electroporationSequence of pathogenic events in cynomolgus macaques infected with aerosolized monkeypox virus.DNA vaccination strategy targets epidermal dendritic cells, initiating their migration and induction of a host immune response.Antibody breadth and protective efficacy are increased by vaccination with computationally optimized hemagglutinin but not with polyvalent hemagglutinin-based H5N1 virus-like particle vaccines.Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation.Enhanced Efficacy of a Codon-Optimized DNA Vaccine Encoding the Glycoprotein Precursor Gene of Lassa Virus in a Guinea Pig Disease Model When Delivered by Dermal Electroporation.Superior induction of T cell responses to conserved HIV-1 regions by electroporated alphavirus replicon DNA compared to that with conventional plasmid DNA vaccine.Intradermal DNA vaccination enhanced by low-current electroporation improves antigen expression and induces robust cellular and humoral immune responses.In vivo molecular imaging and histological analysis of changes induced by electric pulses used for plasmid DNA electrotransfer to the skin: a study in a dorsal window chamber in mice.A vaccinia virus renaissance: new vaccine and immunotherapeutic uses after smallpox eradication.Assessment of the protective effect of Imvamune and Acam2000 vaccines against aerosolized monkeypox virus in cynomolgus macaques.Induction of broad cytotoxic T cells by protective DNA vaccination against Marburg and Ebola.Inducing humoral and cellular responses to multiple sporozoite and liver-stage malaria antigens using exogenous plasmid DNA.Synthetic DNA vaccines: improved vaccine potency by electroporation and co-delivered genetic adjuvants.Toll-Like Receptor 9 Activation Rescues Impaired Antibody Response in Needle-free Intradermal DNA VaccinationGene therapy using plasmid DNA-encoded anti-HER2 antibody for cancers that overexpress HER2.Comparison of intradermal and intramuscular delivery followed by in vivo electroporation of SIV Env DNA in macaques.Optimized and enhanced DNA plasmid vector based in vivo construction of a neutralizing anti-HIV-1 envelope glycoprotein Fab.Skin Transfection Patterns and Expression Kinetics of Electroporation-Enhanced Plasmid Delivery Using the CELLECTRA-3P, a Portable Next-Generation Dermal Electroporation DeviceElectroporation delivery of DNA vaccines: prospects for successOptimizing vaccine development.Animal poxvirus vaccines: a comprehensive review.A review of experimental and natural infections of animals with monkeypox virus between 1958 and 2012.Tapping the Potential of DNA Delivery with Electroporation for Cancer Immunotherapy.Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model.A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin.Efficient delivery of nucleic acid molecules into skin by combined use of microneedle roller and flexible interdigitated electroporation array.
P2860
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P2860
Multivalent smallpox DNA vaccine delivered by intradermal electroporation drives protective immunity in nonhuman primates against lethal monkeypox challenge.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Multivalent smallpox DNA vacci ...... st lethal monkeypox challenge.
@ast
Multivalent smallpox DNA vacci ...... st lethal monkeypox challenge.
@en
Multivalent smallpox DNA vacci ...... st lethal monkeypox challenge.
@nl
type
label
Multivalent smallpox DNA vacci ...... st lethal monkeypox challenge.
@ast
Multivalent smallpox DNA vacci ...... st lethal monkeypox challenge.
@en
Multivalent smallpox DNA vacci ...... st lethal monkeypox challenge.
@nl
prefLabel
Multivalent smallpox DNA vacci ...... st lethal monkeypox challenge.
@ast
Multivalent smallpox DNA vacci ...... st lethal monkeypox challenge.
@en
Multivalent smallpox DNA vacci ...... st lethal monkeypox challenge.
@nl
P2093
P2860
P356
P1476
Multivalent smallpox DNA vacci ...... st lethal monkeypox challenge.
@en
P2093
Abhishek Satishchandran
Amir S Khan
David B Weiner
Erika Hammarlund
Jonathan T Prigge
Lauren A Hirao
Lowrey Rhodes
Maria Yang
Mark Slifka
P2860
P304
P356
10.1093/INFDIS/JIQ017
P407
P577
2011-01-01T00:00:00Z