Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy.
about
HCN1 channel subunits are a molecular substrate for hypnotic actions of ketamine.Searching for new targets for treatment of pediatric epilepsyCortical HCN channels: function, trafficking and plasticityImmediate Epileptogenesis after Kainate-Induced Status Epilepticus in C57BL/6J Mice: Evidence from Long Term Continuous Video-EEG TelemetryHomeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potentialClassic hippocampal sclerosis and hippocampal-onset epilepsy produced by a single “cryptic” episode of focal hippocampal excitation in awake ratsDeletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.Homeostatic regulation of synaptic excitability: tonic GABA(A) receptor currents replace I(h) in cortical pyramidal neurons of HCN1 knock-out mice.Subunit-specific effects of isoflurane on neuronal Ih in HCN1 knockout mice.Mislocalization of h channel subunits underlies h channelopathy in temporal lobe epilepsy.Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis.Development of spontaneous recurrent seizures after kainate-induced status epilepticus.Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsyDown-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy.Sub region-specific modulation of synchronous neuronal burst firing after a kainic acid insult in organotypic hippocampal cultures.HCN Channel Modulation of Synaptic Integration in GABAergic Interneurons in Malformed Rat Neocortex.Downregulation of dendritic HCN channel gating in epilepsy is mediated by altered phosphorylation signaling.Dendritic ion channel trafficking and plasticity.5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders.Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms.Chronic deficit in the expression of voltage-gated potassium channel Kv3.4 subunit in the hippocampus of pilocarpine-treated epileptic ratsCalcium store depletion induces persistent perisomatic increases in the functional density of h channels in hippocampal pyramidal neurons.Altered intrinsic properties of neuronal subtypes in malformed epileptogenic cortex.Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage.HCN channels in behavior and neurological disease: too hyper or not active enough?Initial loss but later excess of GABAergic synapses with dentate granule cells in a rat model of temporal lobe epilepsy.I(h)-mediated depolarization enhances the temporal precision of neuronal integration.Epileptogenesis after prolonged febrile seizures: mechanisms, biomarkers and therapeutic opportunities.Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent mannerThe fast and slow ups and downs of HCN channel regulation.Differential modulation of repetitive firing and synchronous network activity in neocortical interneurons by inhibition of A-type K(+) channels and Ih.Rapid loss of dendritic HCN channel expression in hippocampal pyramidal neurons following status epilepticusDecreased hyperpolarization-activated currents in layer 5 pyramidal neurons enhances excitability in focal cortical dysplasia.Corticospinal-specific HCN expression in mouse motor cortex: I(h)-dependent synaptic integration as a candidate microcircuit mechanism involved in motor controlHCN channelopathies: pathophysiology in genetic epilepsy and therapeutic implicationsImpaired dendritic expression and plasticity of h-channels in the fmr1(-/y) mouse model of fragile X syndrome.Augmented currents of an HCN2 variant in patients with febrile seizure syndromesDefining "epileptogenesis" and identifying "antiepileptogenic targets" in animal models of acquired temporal lobe epilepsy is not as simple as it might seem.The Role of HCN Channels on Membrane Excitability in the Nervous SystemEpigenetic mechanisms in stroke and epilepsy.
P2860
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P2860
Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy.
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Progressive dendritic HCN chan ...... pilocarpine model of epilepsy.
@ast
Progressive dendritic HCN chan ...... pilocarpine model of epilepsy.
@en
Progressive dendritic HCN chan ...... pilocarpine model of epilepsy.
@nl
type
label
Progressive dendritic HCN chan ...... pilocarpine model of epilepsy.
@ast
Progressive dendritic HCN chan ...... pilocarpine model of epilepsy.
@en
Progressive dendritic HCN chan ...... pilocarpine model of epilepsy.
@nl
prefLabel
Progressive dendritic HCN chan ...... pilocarpine model of epilepsy.
@ast
Progressive dendritic HCN chan ...... pilocarpine model of epilepsy.
@en
Progressive dendritic HCN chan ...... pilocarpine model of epilepsy.
@nl
P2093
P2860
P1476
Progressive dendritic HCN chan ...... pilocarpine model of epilepsy.
@en
P2093
Aaron H Sheerin
Anne E Anderson
Joaquin N Lugo
John W Miller
Nicholas P Poolos
Raimondo D'Ambrosio
Sangwook Jung
Terrance D Jones
P2860
P304
13012-13021
P356
10.1523/JNEUROSCI.3605-07.2007
P407
P577
2007-11-01T00:00:00Z