Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?

Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?

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http://www.wikidata.org/entity/Q34937925

Q34937925

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Parallel Aspects of the Microenvironment in Cancer and Autoimmune Disease Enigma of IL-17 and Th17 Cells in Rheumatoid Arthritis and in Autoimmune Animal Models of Arthritis Human genome-wide expression analysis reorients the study of inflammatory mediators and biomechanics in osteoarthritis Presence of IL-17 in synovial fluid identifies a potential inflammatory osteoarthritic phenotype.First-in-human randomized study of bimekizumab, a humanized monoclonal antibody and selective dual inhibitor of IL-17A and IL-17F, in mild psoriasis Infection of Interleukin 17 Receptor A-Deficient C3H Mice with Borrelia burgdorferi Does Not Affect Their Development of Lyme Arthritis and Carditis.Correlation of IL-17 Level in Synovia and Severity of Knee Osteoarthritis.Neutrophils Do Not Express IL-17A in the Context of Acute Oropharyngeal Candidiasis.Lymph node biopsy analysis reveals an altered immunoregulatory balance already during the at-risk phase of autoantibody positive rheumatoid arthritis.The IL-23-IL-17 axis in inflammatory arthritis.Altered immunoregulation in rheumatoid arthritis: the role of regulatory T cells and proinflammatory Th17 cells and therapeutic implications.Progress in understanding and utilizing TNF-α inhibition for the treatment of psoriatic arthritis.Anti-IL-17 therapy in treatment of rheumatoid arthritis: a systematic literature review and meta-analysis of randomized controlled trials.Psoriatic arthritis and psoriasis: differential diagnosis.Secukinumab: A Review in Psoriatic Arthritis.The role of IL 23 in the treatment of psoriasis.Quantitative imaging by pixel-based contrast-enhanced ultrasound reveals a linear relationship between synovial vascular perfusion and the recruitment of pathogenic IL-17A-F+IL-23+ CD161+ CD4+ T helper cells in psoriatic arthritis joints.Synovial membrane receptors as therapeutic targets: A review of receptor localization, structure, and function.A Truncated IL-17RC Peptide Ameliorates Synovitis and Bone Destruction of Arthritic Mice.Follistatin-like protein 1 modulates IL-17 signaling via IL-17RC regulation in stromal cells.Peripheral Ulcerative Keratitis Associated with Autoimmune Disease: Pathogenesis and Treatment.The impact of age and gut microbiota on Th17 and Tfh cells in K/BxN autoimmune arthritis.Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation.Psoriasis pathogenesis and the development of novel targeted immune therapies.Interleukin-17 and Toll-like Receptor 10 genetic polymorphisms and susceptibility to large joint osteoarthritis.Secukinumab in Active Rheumatoid Arthritis: A Phase III Randomized, Double-Blind, Active Comparator- and Placebo-Controlled Study.The role of IL-23 receptor signaling in inflammation-mediated erosive autoimmune arthritis and bone remodeling.Role of the IL-23/IL-17 Axis in Psoriasis and Psoriatic Arthritis: The Clinical Importance of Its Divergence in Skin and Joints.Interleukin-17 in skin: psoriasis and yonder.Characterization of IL-17AA and IL-17FF in rheumatoid arthritis and multiple sclerosis.Fraxinellone Attenuates Rheumatoid Inflammation in Mice.A Reappraisal on the Potential Ability of Human Neutrophils to Express and Produce IL-17 Family Members In Vitro: Failure to Reproducibly Detect It.[Psoriatic arthritis : Drugs of the (near) future].Plasma miR-136 can be used to screen patients with knee osteoarthritis from healthy controls by targeting IL-17

P2860

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P2860

Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?

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http://www.wikidata.org/entity/Q34937925

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2014 nî lūn-bûn

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2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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