Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.
about
FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complexDevelopment of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinasesMatrix Metalloproteinases in Non-Neoplastic Disorders.Drugs derived from phage display: from candidate identification to clinical practiceMoving targets: Emerging roles for MMPs in cancer progression and metastasisQuantitative FRET imaging to visualize the invasiveness of live breast cancer cellsTargeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging GliomasHedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active SiteA Reverse Binding Motif That Contributes to Specific Protease Inhibition by AntibodiesAntibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potentialMMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglinTransducer of Cdc42-dependent actin assembly promotes breast cancer invasion and metastasis.Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia.Ensnaring membrane type 1-matrix metalloproteinase (MT1-MMP) with tissue inhibitor of metalloproteinase (TIMP)-2 using the haemopexin domain of the protease as a carrier: a targeted approach in cancer inhibition.Membrane-associated matrix proteolysis and heart failure.Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions.Selective matrix metalloproteinase (MMP) inhibitors in cancer therapy: ready for prime time?Endoglin in liver fibrogenesis: Bridging basic science and clinical practiceDirected evolution of protease beacons that enable sensitive detection of endogenous MT1-MMP activity in tumor cell lines.Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer.Shedding of RANKL by tumor-associated MT1-MMP activates Src-dependent prostate cancer cell migration.Metalloproteinase binding proteins: WO2009097397.Rho-ROCK-myosin signaling mediates membrane type 1 matrix metalloproteinase-induced cellular aggregation of keratinocytes.Matrix metalloproteinases in tumorigenesis: an evolving paradigm.Emerging principles in protease-based drug discovery.PEGylation extends circulation half-life while preserving in vitro and in vivo activity of tissue inhibitor of metalloproteinases-1 (TIMP-1)Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisitedMatrix metalloproteinase-14 both sheds cell surface neuronal glial antigen 2 (NG2) proteoglycan on macrophages and governs the response to peripheral nerve injuryMatrix metalloproteinases: protective roles in cancer.Specific matrix metalloproteinases play different roles in intraplaque angiogenesis and plaque instability in rabbits.Inhibition of matrix metalloproteinase 14 (MMP-14)-mediated cancer cell migration.Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy.Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosisNew strategies for targeting matrix metalloproteinasesPhosphoramidate-based peptidomimetic inhibitors of membrane type-1 matrix metalloproteinaseTargeting invadopodia to block breast cancer metastasisIdentification of Reprogrammed Myeloid Cell Transcriptomes in NSCLCContribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progressionTargeting Matrix Metalloproteinases in Cancer: Bringing New Life to Old IdeasMatrix metalloproteinases as breast cancer drivers and therapeutic targets.
P2860
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P2860
Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Selective inhibition of matrix ...... h, invasion, and angiogenesis.
@ast
Selective inhibition of matrix ...... h, invasion, and angiogenesis.
@en
Selective inhibition of matrix ...... h, invasion, and angiogenesis.
@nl
type
label
Selective inhibition of matrix ...... h, invasion, and angiogenesis.
@ast
Selective inhibition of matrix ...... h, invasion, and angiogenesis.
@en
Selective inhibition of matrix ...... h, invasion, and angiogenesis.
@nl
prefLabel
Selective inhibition of matrix ...... h, invasion, and angiogenesis.
@ast
Selective inhibition of matrix ...... h, invasion, and angiogenesis.
@en
Selective inhibition of matrix ...... h, invasion, and angiogenesis.
@nl
P2093
P1433
P1476
Selective inhibition of matrix ...... th, invasion, and angiogenesis
@en
P2093
Andrew E Nixon
Annabelle Lejeune
Chris Tenhoor
Clive R Wood
Csaba Pazmany
Daniel T Dransfield
Douglas Rank
Edward Chang
Guannan Kuang
Henk Pieters
P304
P356
10.1158/0008-5472.CAN-08-3255
P407
P577
2009-02-10T00:00:00Z