Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
about
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4EFibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathwaysTuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signalingTumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinaseSirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsRegulation of mTORC1 by PI3K signalingBidirectional transport of amino acids regulates mTOR and autophagyERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functionsTarget of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progressionInorganic polyphosphate stimulates mammalian TOR, a kinase involved in the proliferation of mammary cancer cells.Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A.Luteinizing hormone stimulates mammalian target of rapamycin signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase: modulation of glycogen synthase kinase 3 and AMP-activated protein kinaseLovastatin induces VSMC differentiation through inhibition of Rheb and mTOR.Cullin-1 promotes cell proliferation via cell cycle regulation and is a novel in prostate cancer.P70S6K 1 regulation of angiogenesis through VEGF and HIF-1alpha expressionThe complexes of mammalian target of rapamycin.β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathwayNiacin activates the PI3K/Akt cascade via PKC- and EGFR-transactivation-dependent pathways through hydroxyl-carboxylic acid receptor 2.A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila.Akt Regulates TNFα synthesis downstream of RIP1 kinase activation during necroptosis.Phosphate sensing.Combination of rapamycin, CI-1040, and 17-AAG inhibits metastatic capacity of prostate cancer via Slug inhibition.Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1).Candidate mechanisms accounting for effects of physical activity on breast carcinogenesis.Proteomic analysis of immediate-early response plasma proteins after 70% and 90% partial hepatectomy.PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axisThe impact of S6K1 kinase on neuroblastoma cell proliferation is independent of GLI1 signalingA Phase I/II Study of the mTOR Inhibitor Everolimus in Combination with HyperCVAD Chemotherapy in Patients with Relapsed/Refractory Acute Lymphoblastic LeukemiaAssociation of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric CancerSmall molecule and monoclonal antibody therapies in neurooncology.Lysine-specific demethylase 1 mediates epidermal growth factor signaling to promote cell migration in ovarian cancer cells.The role of S6K1 in ER-positive breast cancer.Transforming Growth Factor β1-induced Apoptosis in Podocytes via the Extracellular Signal-regulated Kinase-Mammalian Target of Rapamycin Complex 1-NADPH Oxidase 4 AxisBaculovirus-mediated expression, purification, and characterization of a fully activated catalytic kinase domain construct of the 70 kDa 40S ribosomal protein S6 kinase-1 alphaII isoform (S6K1alphaII).Expression, purification, and characterization of a structurally disordered and functional C-terminal autoinhibitory domain (AID) of the 70 kDa 40S ribosomal protein S6 kinase-1 (S6K1).Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancerAMPK represses TOP mRNA translation but not global protein synthesis in liverDietary energy restriction modulates the activity of AMP-activated protein kinase, Akt, and mammalian target of rapamycin in mammary carcinomas, mammary gland, and liver.Effect of rapamycin on endometriosis in mice.Activation of signaling pathways and regulatory mechanisms of mRNA translation following myocardial ischemia-reperfusion.
P2860
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P2860
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
@ast
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
@en
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
@nl
type
label
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
@ast
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
@en
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
@nl
prefLabel
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
@ast
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
@en
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
@nl
P1476
Coordinate regulation of translation by the PI 3-kinase and mTOR pathways.
@en
P2093
John Blenis
Kathleen A Martin
P356
10.1016/S0065-230X(02)86001-8
P577
2002-01-01T00:00:00Z