Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo - Wikidata - wikimedia - TriplyDB

Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo

Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo

http://www.wikidata.org/entity/Q34961411

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Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells The astrocyte odyssey Metabolic and hemodynamic events after changes in neuronal activity: current hypotheses, theoretical predictions and in vivo NMR experimental findings.Exercise Counteracts Aging-Related Memory Impairment: A Potential Role for the Astrocytic Metabolic Shuttle Reevaluating Metabolism in Alzheimer's Disease from the Perspective of the Astrocyte-Neuron Lactate Shuttle Model Unraveling the complex metabolic nature of astrocytes The Warburg effect: 80 years on Food for thought: challenging the dogmas Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis Determinants of brain cell metabolic phenotypes and energy substrate utilization unraveled with a modeling approach Cerebral Developmental Abnormalities in a Mouse with Systemic Pyruvate Dehydrogenase Deficiency.Astrocyte-neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions--in silico study supported by in vitro expression data Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis.Evidence for the mitochondrial lactate oxidation complex in rat neurons: demonstration of an essential component of brain lactate shuttles Fatty acids in energy metabolism of the central nervous system Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation.Hyperglycaemia and diabetes impair gap junctional communication among astrocytes.Regulation of pyruvate metabolism and human disease Role of monocarboxylate transporters in drug delivery to the brain.Amyloid beta resistance in nerve cell lines is mediated by the Warburg effect.Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons.An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.Brain lactate kinetics: Modeling evidence for neuronal lactate uptake upon activation PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism Methylglyoxal, the dark side of glycolysis Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase Energy substrates for neurons during neural activity: a critical review of the astrocyte-neuron lactate shuttle hypothesis.Effects of L-glutamate/D-aspartate and monensin on lactic acid production in retina and cultured retinal Müller cells.Neurometabolic coupling between neural activity, glucose, and lactate in activated visual cortex.Age-related metabolic fatigue during low glucose conditions in rat hippocampus.Neuroenergetics: calling upon astrocytes to satisfy hungry neurons.The return of metabolism: biochemistry and physiology of the pentose phosphate pathway Neural Stem Cells in the Adult Subventricular Zone Oxidize Fatty Acids to Produce Energy and Support Neurogenic Activity Sweet sixteen for ANLS.BACE1 activity impairs neuronal glucose oxidation: rescue by beta-hydroxybutyrate and lipoic acid.Lactate as a biomarker for sleep.Lactate: the ultimate cerebral oxidative energy substrate?Neuronal-glial glucose oxidation and glutamatergic-GABAergic function.The physiological and biochemical bases of functional brain imaging.Primary cultures of astrocytes: their value in understanding astrocytes in health and disease.

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P2860

Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo

http://www.wikidata.org/entity/Q34961411

description

2003 nî lūn-bûn

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2003 թուականի Մարտին հրատարակուած գիտական յօդուած

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2003 թվականի մարտին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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Dichloroacetate effects on glu ...... e utilization by brain in vivo

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Dichloroacetate effects on glu ...... e utilization by brain in vivo

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Dichloroacetate effects on glu ...... e utilization by brain in vivo

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Dichloroacetate effects on glu ...... e utilization by brain in vivo

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Dichloroacetate effects on glu ...... e utilization by brain in vivo

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Dichloroacetate effects on glu ...... e utilization by brain in vivo

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Proceedings of the National Academy of Sciences of the United States of America

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Dichloroacetate effects on glu ...... e utilization by brain in vivo

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P2093

Elaine Kaufman

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Kazuaki Shimoji

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Louis Sokoloff

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Michelle Cook

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Mona J Law

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Takanori Esaki

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Yoshiaki Itoh

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P2860

Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation

Measurement of protein using bicinchoninic acid

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization

Cellular mechanisms of brain energy metabolism and their relevance to functional brain imaging.

The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat.

Role of sodium and potassium ions in regulation of glucose metabolism in cultured astroglia.

Do active cerebral neurons really use lactate rather than glucose?

Synopsis of the workshop entitled "Is lactate a nutrient for neurons" held at the Brain Energy Meeting in Trondheim, Norway.

Glucose and lactate metabolism during brain activation.

Treatment of congenital lactic acidosis with dichloroacetate.

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10.1073/PNAS.0831078100

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8

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dichloroacetate

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