A small molecule that directs differentiation of human ESCs into the pancreatic lineage. - Wikidata - wikimedia - TriplyDB

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

http://www.wikidata.org/entity/Q34962844

about

Insulin-secreting β cells require a post-genomic concept Recent Advances in Disease Modeling and Drug Discovery for Diabetes Mellitus Using Induced Pluripotent Stem Cells Knowledge Gaps in Rodent Pancreas Biology: Taking Human Pluripotent Stem Cell-Derived Pancreatic Beta Cells into Our Own Hands Stem Cells and Regenerative Medicine: Myth or Reality of the 21th Century Histone Deacetylases and Cardiometabolic Diseases Advances and challenges in the differentiation of pluripotent stem cells into pancreatic β cells Proteins and small molecules for cellular regenerative medicine Pancreatic stem cells remain unresolved Concise review: A chemical approach to control cell fate and function Pluripotent stem cells in regenerative medicine: challenges and recent progress Concise review: pancreas regeneration: recent advances and perspectives Small molecule-driven direct conversion of human pluripotent stem cells into functional osteoblasts Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis A stem cell-based tool for small molecule screening in adipogenesis Modulation of the pentose phosphate pathway induces endodermal differentiation in embryonic stem cells Efficient and rapid induction of human iPSCs/ESCs into nephrogenic intermediate mesoderm using small molecule-based differentiation methods Skin fibroblasts from patients with type 1 diabetes (T1D) can be chemically transdifferentiated into insulin-expressing clusters: a transgene-free approach Small-molecule inhibitors of the cystic fibrosis transmembrane conductance regulator increase pancreatic endocrine cell development in rat and mouse Directed differentiation of human iPSC into insulin producing cells is improved by induced expression of PDX1 and NKX6.1 factors in IPC progenitors Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.High content screening for modulators of cardiac differentiation in human pluripotent stem cells Chemical approaches to stem cell biology and therapeutics Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation.Stem cell biology and drug discovery.A design strategy for drug-like polyheterocycles with privileged substructures for discovery of specific small-molecule modulators.High-throughput screening in embryonic stem cell-derived neurons identifies potentiators of alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate-type glutamate receptors.Embryonic stem cell application in drug discovery.Controlling destiny through chemistry: small-molecule regulators of cell fate.Total syntheses of indolactam alkaloids (-)-indolactam V, (-)-pendolmycin, (-)-lyngbyatoxin A, and (-)-teleocidin A-2.A multi-parameter, high-content, high-throughput screening platform to identify natural compounds that modulate insulin and Pdx1 expression.Regenerating pancreatic beta-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis.Bioinspired materials for controlling stem cell fate.Current status of islet cell replacement and regeneration therapy.Stem Cell Therapy: A New Treatment for Burns?Recent advances in pancreas development: from embryonic pathways to programming renewable sources of beta cells Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directions.Switching of mesodermal and endodermal properties in hTERT-modified and expanded fetal human pancreatic progenitor cells.Regenerative chemical biology: current challenges and future potential A screen for regulators of survival of motor neuron protein levels Glial cell line-derived neurotrophic factor enhances neurogenin3 gene expression and beta-cell proliferation in the developing mouse pancreas.

P2860

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P2860

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

http://www.wikidata.org/entity/Q34962844

description

2009 nî lūn-bûn

@nan

2009 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի մարտին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

@ast

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

@en

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

@nl

type

label

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

@ast

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

@en

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

@nl

prefLabel

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

@ast

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

@en

A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

@nl

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P1433

Nature Chemical Biology

P1476

A small molecule that directs differentiation of human ESCs into the pancreatic lineage

@en

P2093

Douglas Melton

http://www.w3.org/2001/XMLSchema#string

Julia L Fox

http://www.w3.org/2001/XMLSchema#string

Kelvin Lam

http://www.w3.org/2001/XMLSchema#string

Kenji Osafune

http://www.w3.org/2001/XMLSchema#string

Lance Davidow

http://www.w3.org/2001/XMLSchema#string

Lee F Peng

http://www.w3.org/2001/XMLSchema#string

Malgorzata Borowiak

http://www.w3.org/2001/XMLSchema#string

René Maehr

http://www.w3.org/2001/XMLSchema#string

Shuibing Chen

http://www.w3.org/2001/XMLSchema#string

Stuart L Schreiber

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P2888

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258-265

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scholarly article

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10.1038/NCHEMBIO.154

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4

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5

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2009-03-15T00:00:00Z

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24201899

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19287398

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