Molecular diagnostic profiling of lung cancer specimens with a semiconductor-based massive parallel sequencing approach: feasibility, costs, and performance compared with conventional sequencing.
about
Assessing copy number alterations in targeted, amplicon-based next-generation sequencing data.Ioncopy: a novel method for calling copy number alterations in amplicon sequencing data including significance assessment.Clinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer.Mutations in BRCA2 and taxane resistance in prostate cancerTargeted ultra-deep sequencing reveals recurrent and mutually exclusive mutations of cancer genes in blastic plasmacytoid dendritic cell neoplasm.Highly sensitive amplicon-based transcript quantification by semiconductor sequencingMutational profiles in triple-negative breast cancer defined by ultradeep multigene sequencing show high rates of PI3K pathway alterations and clinically relevant entity subgroup specific differences.Development of a semi-conductor sequencing-based panel for genotyping of colon and lung cancer by the Onconetwork consortiumRetrospective review using targeted deep sequencing reveals mutational differences between gastroesophageal junction and gastric carcinomas.Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.Comprehensive Molecular Profiling of Archival Bone Marrow Trephines Using a Commercially Available Leukemia Panel and Semiconductor-Based Targeted ResequencingUtility of different massive parallel sequencing platforms for mutation profiling in clinical samples and identification of pitfalls using FFPE tissueClinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers.Building a Robust Tumor Profiling Program: Synergy between Next-Generation Sequencing and Targeted Single-Gene TestingCytology smears as excellent starting material for next-generation sequencing-based molecular testing of patients with adenocarcinoma of the lung.Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.Genetic changes of non-small cell lung cancer under neoadjuvant therapyRoutine clinical mutation profiling using next generation sequencing and a customized gene panel improves diagnostic precision in myeloid neoplasms.Molecular driver alterations and their clinical relevance in cancer of unknown primary site.MET expression and copy number status in clear-cell renal cell carcinoma: prognostic value and potential predictive marker.Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines.Next generation diagnostic molecular pathology: critical appraisal of quality assurance in Europe.Molecular pathology in lung cancer: a guide to the techniques used in clinical practice.Spatial distribution of EGFR and KRAS mutation frequencies correlates with histological growth patterns of lung adenocarcinomas.CCI-779 (Temsirolimus) exhibits increased anti-tumor activity in low EGFR expressing HNSCC cell lines and is effective in cells with acquired resistance to cisplatin or cetuximabIndividualized medicine and demographic change as determining workload factors in pathology: quo vadis?Colorectal mixed adenoneuroendocrine carcinomas and neuroendocrine carcinomas are genetically closely related to colorectal adenocarcinomas.Targeted next-generation sequencing enables reliable detection of HER2 (ERBB2) status in breast cancer and provides ancillary information of clinical relevance.Synonymous EGFR variant p.Q787Q is neither prognostic nor predictive in patients with lung adenocarcinoma.Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes.Tubular, lactating, and ductal adenomas are devoid of MED12 Exon2 mutations, and ductal adenomas show recurrent mutations in GNAS and the PI3K-AKT pathway.Genotyping of colorectal cancer for cancer precision medicine: Results from the IPH Center for Molecular Pathology.Mutations in genes encoding PI3K-AKT and MAPK signaling define anogenital papillary hidradenoma.Molecular signaling in multiple myeloma: association of RAS/RAF mutations and MEK/ERK pathway activation.Immunoglobulin rearrangement analysis from multiple lesions in the same patient using next-generation sequencing.Semiconductor-based sequencing of formalin-fixed, paraffin-embedded colorectal cancer samples.KIT mutations in primary mediastinal B-cell lymphoma.[Novel morphological and molecular aspects of lung cancer].Oncogenic driver mutations, treatment, and EGFR-TKI resistance in a Caucasian population with non-small cell lung cancer: survival in clinical practice.Targeted deep sequencing of effusion cytology samples is feasible, informs spatiotemporal tumor evolution, and has clinical and diagnostic utility.
P2860
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P2860
Molecular diagnostic profiling of lung cancer specimens with a semiconductor-based massive parallel sequencing approach: feasibility, costs, and performance compared with conventional sequencing.
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Molecular diagnostic profiling ...... with conventional sequencing.
@ast
Molecular diagnostic profiling ...... with conventional sequencing.
@en
Molecular diagnostic profiling ...... with conventional sequencing.
@nl
type
label
Molecular diagnostic profiling ...... with conventional sequencing.
@ast
Molecular diagnostic profiling ...... with conventional sequencing.
@en
Molecular diagnostic profiling ...... with conventional sequencing.
@nl
prefLabel
Molecular diagnostic profiling ...... with conventional sequencing.
@ast
Molecular diagnostic profiling ...... with conventional sequencing.
@en
Molecular diagnostic profiling ...... with conventional sequencing.
@nl
P2093
P1476
Molecular diagnostic profiling ...... with conventional sequencing.
@en
P2093
Albrecht Stenzinger
Alexander Muckenhuber
Peter Schirmacher
Roland Penzel
Volker Endris
P304
P356
10.1016/J.JMOLDX.2013.06.002
P577
2013-08-21T00:00:00Z