Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. - Wikidata - wikimedia - TriplyDB

Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.

Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.

http://www.wikidata.org/entity/Q34970100

about

Single-cell technologies to study the immune system Long Intergenic Non-Coding RNAs: Novel Drivers of Human Lymphocyte Differentiation The Differentiation of CD4(+) T-Helper Cell Subsets in the Context of Helminth Parasite Infection S. mansoni bolsters anti-viral immunity in the murine respiratory tract Boi-ogi-to (TJ-20), a Kampo Formula, Suppresses the Inflammatory Bone Destruction and the Expression of Cytokines in the Synovia of Ankle Joints of Adjuvant Arthritic Rats.Th2/1 Hybrid Cells Occurring in Murine and Human Strongyloidiasis Share Effector Functions of Th1 Cells Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.An animated landscape representation of CD4+ T-cell differentiation, variability, and plasticity: insights into the behavior of populations versus cells A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection.Mapping differentiation under mixed culture conditions reveals a tunable continuum of T cell fates Stochastic cytokine expression induces mixed T helper cell States.Hybrid T-helper cells: stabilizing the moderate center in a polarized system.Model checking to assess T-helper cell plasticity.Cellular Plasticity of CD4+ T Cells in the Intestine.IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells A Mathematical Framework for Understanding Four-Dimensional Heterogeneous Differentiation of CD4+ T Cells T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production.Individual T helper cells have a quantitative cytokine memory Avidity of human T cell receptor engineered CD4(+) T cells drives T-helper differentiation fate Enrichment of IFN-γ producing cells in different murine adipose tissue depots upon infection with an apicomplexan parasite Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells Susceptibility to Ticks and Lyme Disease Spirochetes Is Not Affected in Mice Coinfected with Nematodes.TGF-β/BAMBI pathway dysfunction contributes to peripheral Th17/Treg imbalance in chronic obstructive pulmonary disease Plasticity of human CD4 T cell subsets Host regulation of liver fibroproliferative pathology during experimental schistosomiasis via interleukin-4 receptor alpha Translational opportunities for targeting the Th17 axis in acute graft-vs.-host disease.IL-4Rα on dendritic cells in neonates and Th2 immunopathology in respiratory syncytial virus infection.T-cell clones in human trichinellosis: Evidence for a mixed Th1/Th2 response.Dynamic balance between master transcription factors determines the fates and functions of CD4 T cell and innate lymphoid cell subsets.Epigenetic regulation of T-helper cell differentiation, memory, and plasticity in allergic asthma.Quantitative Proteomics of Gut-Derived Th1 and Th1/Th17 Clones Reveal the Presence of CD28+ NKG2D- Th1 Cytotoxic CD4+ T cells Toxoplasma Co-infection Prevents Th2 Differentiation and Leads to a Helminth-Specific Th1 Response.Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4+ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation.Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships.Up-regulation of MDP and tuftsin gene expression in Th1 and Th17 cells as an adjuvant for an oral Lactobacillus casei vaccine against anti-transmissible gastroenteritis virus.Insufficient interleukin-12 signalling favours differentiation of human CD4(+) and CD8(+) T cells into GATA-3(+) and GATA-3(+) T-bet(+) subsets in humanized mice.Human amnion favours tissue repair by inducing the M1-to-M2 switch and enhancing M2 macrophage features.Effector/memory CD4 T cells making either Th1 or Th2 cytokines commonly co-express T-bet and GATA-3.Diverse continuum of CD4+ T-cell states is determined by hierarchical additive integration of cytokine signals.CD96 expression determines the inflammatory potential of IL-9-producing Th9 cells.

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Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.

http://www.wikidata.org/entity/Q34970100

description

2013 nî lūn-bûn

@nan

2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի օգոստոսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Stable T-bet(+)GATA-3(+) Th1/T ...... immunopathologic inflammation.

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Stable T-bet(+)GATA-3(+) Th1/T ...... immunopathologic inflammation.

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Stable T-bet(+)GATA-3(+) Th1/T ...... immunopathologic inflammation.

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type

label

Stable T-bet(+)GATA-3(+) Th1/T ...... immunopathologic inflammation.

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Stable T-bet(+)GATA-3(+) Th1/T ...... immunopathologic inflammation.

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Stable T-bet(+)GATA-3(+) Th1/T ...... immunopathologic inflammation.

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prefLabel

Stable T-bet(+)GATA-3(+) Th1/T ...... immunopathologic inflammation.

@ast

Stable T-bet(+)GATA-3(+) Th1/T ...... immunopathologic inflammation.

@en

Stable T-bet(+)GATA-3(+) Th1/T ...... immunopathologic inflammation.

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JOURNAL.PBIO.1001633

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Stable T-bet(+)GATA-3(+) Th1/T ...... immunopathologic inflammation

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Ahmed N Hegazy

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Anja A Kühl

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Anja Fröhlich

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Caroline Helmstetter

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Christoph G Grevelding

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Sebastian Rausch

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Susanne Hartmann

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P2860

A novel transcription factor, T-bet, directs Th1 lineage commitment

Functional role of type I and type II interferons in antiviral defense

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo

Fate mapping of IL-17-producing T cells in inflammatory responses

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

Genomic views of STAT function in CD4+ T helper cell differentiation

T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

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10.1371/JOURNAL.PBIO.1001633

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