Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b.
about
The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentationRegulation of Lipid Specific and Vitamin Specific Non-MHC Restricted T Cells by Antigen Presenting Cells and Their Therapeutic PotentialsCD1 and mycobacterial lipids activate human T cellsLipid presentation by human CD1 molecules and the diverse T cell populations that respond to themThe CD1 size problem: lipid antigens, ligands, and scaffoldsRelationships between Th1 or Th2 iNKT cell activity and structures of CD1d-antigen complexes: meta-analysis of CD1d-glycolipids dynamics simulationsStructural Basis for Lipid-Antigen Recognition in Avian ImmunityCrystal Structure of Bovine CD1b3 with Endogenously Bound LigandsStructure of a Classical MHC Class I Molecule That Binds “Non-Classical” LigandsCrystal structure of human CD1e reveals a groove suited for lipid-exchange processesNatural lipid ligands associated with human CD1d targeted to different subcellular compartmentsThe T-Cell Response to Lipid Antigens of Mycobacterium tuberculosisA novel self-lipid antigen targets human T cells against CD1c(+) leukemiasLipid antigens in immunity.Phage display of functional αβ single-chain T-cell receptor molecules specific for CD1b:Ac₂SGL complexes from Mycobacterium tuberculosis-infected cellsPresentation of lipid antigens by CD1 glycoproteins.CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humansIdentification of self-lipids presented by CD1c and CD1d proteins.Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipidsDiscovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system.Human autoreactive T cells recognize CD1b and phospholipidsHow T lymphocytes recognize lipid antigens.CD1 mediated T cell recognition of glycolipids.Dynamics of the antigen-binding grooves in CD1 proteins: reversible hydrophobic collapse in the lipid-free state.pH-dependent interdomain tethers of CD1b regulate its antigen capture.CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens.Primary immunodeficiency associated with defects in CD1 and CD1-restricted T cells.T cells specific for lipid antigens.Molecular basis of lipid antigen presentation by CD1d and recognition by natural killer T cells.Group 1 CD1-restricted T cells and the pathophysiological implications of self-lipid antigen recognition.CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails.The CD1 family: serving lipid antigens to T cells since the Mesozoic era.Donor-unrestricted T cells in the human CD1 system.Molecular recognition of microbial lipid-based antigens by T cells.The Conventional Nature of Non-MHC-Restricted T Cells.
P2860
Q24317551-D7A8DA3C-FAD3-4272-98F8-E82B9177A6CCQ26797333-E78BCDB7-2C6F-4F9D-9509-7DF6193D45F8Q26863207-39B7938D-4C4F-4AC6-92C1-22B237CCCB0AQ26996562-53BE9D8C-5257-4CBB-A930-58026881F7C1Q27024188-8C462F60-2775-4BFC-9987-E84D4C051647Q27320844-57E4FECB-0908-430F-B63A-11F795CDC486Q27659192-3B7B0AAF-C9FE-4C4D-AC48-8306D4738413Q27662107-F03A0AF5-2625-400B-9190-A82A638D4EAFQ27666285-0E39FEC0-3352-4F04-8A18-E18A63CAD6A5Q27671006-2150D0FB-B385-4D29-A1CA-10414F830B03Q33426265-E456443C-A680-46BF-9F11-9A4E056138A0Q33658959-3AAD7FB8-F30F-4740-BFE1-41BAB4155553Q33826848-336A4C05-F473-4636-967B-F50B5F33249DQ34025822-2BA58D7B-673C-44E1-9D37-A1D0674D3E3CQ34607534-84D1BD56-5926-443D-A9EB-ADB1D9958A7EQ34987421-F6E632B2-B3EA-45A9-BC5B-5838185E4BC9Q35208379-B6D3DC13-36EC-4403-A78E-2099F31C8977Q35424025-ACBBA8C8-5C83-4E3A-861B-AA2002A29A71Q35470808-805A3598-8443-449F-9442-4465766582CCQ35585671-878B912A-89FA-43C0-A469-9CAEC07622DAQ36483318-8EEB2DE3-EC0C-4C37-9C64-55A0BF708D42Q36584187-1746F961-7BF7-41DF-8B1A-AF32783EAB7AQ36976919-2B30D020-E470-4CFB-AC60-AAEE32677B35Q37000542-06229A8A-08D7-4BE5-8EE8-F564DF5EF633Q37366376-96BF2019-3FAB-4176-9F30-BE63266CB53BQ37599571-BE063790-DC4C-49AA-BCB4-553A53F8EFCFQ37978654-2B8A2283-C13A-4B3B-BB7E-A3ED2CFDC391Q37994621-B6AE44F9-DC69-4519-9954-E2F6893B01C3Q38050484-365189CE-7D89-4770-9F00-E3BF9BABD8DFQ38619546-45DCD139-888D-4E03-A54B-942ED4E83F09Q38664518-D841099F-F2F0-4E02-9044-474C1AECA2DCQ38883512-EDF6FD04-B3A6-43CC-A63B-94B950847904Q38922079-BFDBC0E0-17D8-4C85-8A56-5D3D9575C38CQ47728419-5653F81B-9BE3-44C1-B224-7E5BAA769584Q55399719-094E2243-0423-4EB7-9DB8-69E119C78534
P2860
Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Endogenous phosphatidylcholine ...... lipid-binding groove of CD1b.
@ast
Endogenous phosphatidylcholine ...... lipid-binding groove of CD1b.
@en
Endogenous phosphatidylcholine ...... lipid-binding groove of CD1b.
@nl
type
label
Endogenous phosphatidylcholine ...... lipid-binding groove of CD1b.
@ast
Endogenous phosphatidylcholine ...... lipid-binding groove of CD1b.
@en
Endogenous phosphatidylcholine ...... lipid-binding groove of CD1b.
@nl
prefLabel
Endogenous phosphatidylcholine ...... lipid-binding groove of CD1b.
@ast
Endogenous phosphatidylcholine ...... lipid-binding groove of CD1b.
@en
Endogenous phosphatidylcholine ...... lipid-binding groove of CD1b.
@nl
P2093
P2860
P50
P356
P1433
P1476
Endogenous phosphatidylcholine ...... lipid-binding groove of CD1b.
@en
P2093
Albert J R Heck
Ana Tesouro Vallina
Hans-Jürgen Gober
Kees Versluis
Lionel Mourey
Lucia Mori
Luis F Garcia-Alles
Nana Fatimath Bello
Sebastiano Sansano
Valérie Guillet
P2860
P304
P356
10.1038/SJ.EMBOJ.7601244
P407
P577
2006-07-27T00:00:00Z