The structures of integrins and integrin-ligand complexes: implications for drug design and signal transduction.
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Calpha-H...O = C hydrogen bonds contribute to the specificity of RGD cell-adhesion interactionsRadiolabeled Cyclic RGD Peptide Bioconjugates as Radiotracers Targeting Multiple IntegrinsEnhanced Specificity and Drug Delivery in Tumors by cRGD-Anchoring Thermosensitive LiposomesStructural basis for distinctive recognition of fibrinogen γC peptide by the platelet integrin α IIb β 3Radiolabeled cyclic RGD peptides as radiotracers for tumor imagingDesign, synthesis, and evaluation of near infrared fluorescent multimeric RGD peptides for targeting tumorsResonant infrared multiphoton dissociation spectroscopy of gas-phase protonated peptides. Experiments and Car-Parrinello dynamics at 300 K.Peptide-mediated cellular uptake of cryptophane.Insight into nanoparticle cellular uptake and intracellular targetingAn easily accessible sulfated saccharide mimetic inhibits in vitro human tumor cell adhesion and angiogenesis of vascular endothelial cells.Radiolabeled Cyclic RGD Peptides as Radiotracers for Imaging Tumors and Thrombosis by SPECTTumor targeting, trifunctional dendritic wedge.Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeuticsStructural flexibility of small GTPases. Can it explain their functional versatility?Synthesis, Characterization, and Biological Evaluation of a Dual-Action Ligand Targeting αvβ3 Integrin and VEGF ReceptorsTargeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances.Synthesis, characterization, and biological evaluation of integrin alphavbeta3-targeted PAMAM dendrimers.Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers.Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency.Interaction and conformational dynamics of membrane-spanning protein helices.Protein damage in diabetes and uremia--identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect.Radiometallated peptides for molecular imaging and targeted therapy.Precision polymers--modern tools to understand and program macromolecular interactions.Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics.Drug delivery and release systems for targeted tumor therapy.αvβ3- or α5β1-Integrin-Selective Peptidomimetics for Surface Coating.An integrin-targeted photoactivatable Pt(IV) complex as a selective anticancer pro-drug: synthesis and photoactivation studies.Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers.Integrin-targeted delivery into cancer cells of a Pt(IV) pro-drug through conjugation to RGD-containing peptides.Cyclic RGD peptides interfere with binding of the Helicobacter pylori protein CagL to integrins αVβ3 and α5β1.Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin.Tumor Targeting with an isoDGR-Drug ConjugateExploring the Role of RGD-Recognizing Integrins in Cancer.Combined QM/MM study of thyroid and steroid hormone analogue interactions with αvβ3 integrin.Nanoscale Adhesion Ligand Organization Regulates Osteoblast Proliferation and Differentiation.Cyclic RGD-peptidomimetics containing bifunctional diketopiperazine scaffolds as new potent integrin ligands.Self-assembled multivalent RGD-peptide arrays--morphological control and integrin binding.The parent anion of the RGD tripeptide: Photoelectron spectroscopy and quantum chemistry calculations.Cyclic-RGD penta-peptides cRGDyK derivatized with cyclopentadienyl complexes of technetium and rhenium as radiopharmaceutical probes.Differential diagnosis of solitary pulmonary nodules using ⁹⁹mTc-3P₄-RGD₂ scintigraphy.
P2860
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P2860
The structures of integrins and integrin-ligand complexes: implications for drug design and signal transduction.
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The structures of integrins an ...... esign and signal transduction.
@ast
The structures of integrins an ...... esign and signal transduction.
@en
The structures of integrins an ...... esign and signal transduction.
@nl
type
label
The structures of integrins an ...... esign and signal transduction.
@ast
The structures of integrins an ...... esign and signal transduction.
@en
The structures of integrins an ...... esign and signal transduction.
@nl
prefLabel
The structures of integrins an ...... esign and signal transduction.
@ast
The structures of integrins an ...... esign and signal transduction.
@en
The structures of integrins an ...... esign and signal transduction.
@nl
P1433
P1476
The structures of integrins an ...... esign and signal transduction.
@en
P2093
Horst Kessler
Kay-E Gottschalk
P304
P356
10.1002/1521-3773(20021018)41:20<3767::AID-ANIE3767>3.0.CO;2-T
P577
2002-10-01T00:00:00Z