A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
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Mechanism of Cd2+ Coordination during Slow Inactivation in Potassium ChannelsProtein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeationUsing protein backbone mutagenesis to dissect the link between ion occupancy and C-type inactivation in K+ channelsDeterminants of cation transport selectivity: Equilibrium binding and transport kineticsA molecular switch driving inactivation in the cardiac K+ channel HERGComprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates.Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.Initial steps of inactivation at the K+ channel selectivity filterA self-consistent approach for determining pairwise interactions that underlie channel activation.Visualizing KcsA conformational changes upon ion binding by infrared spectroscopy and atomistic modeling.Altered and dynamic ion selectivity of K+ channels in cell development and excitabilityA structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.The Role of the Carboxyl Terminus Helix C-D Linker in Regulating KCNQ3 K+ Current Amplitudes by Controlling Channel TraffickingTWIK1, a unique background channel with variable ion selectivity.Pore helix-S6 interactions are critical in governing current amplitudes of KCNQ3 K+ channels.Pore determinants of KCNQ3 K+ current expression.Residues at the outer mouth of Kir1.1 determine K-dependent gating.Metabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains.Protonation state of E71 in KcsA and its role for channel collapse and inactivation.Perspectives on: conformational coupling in ion channels: thermodynamics of electromechanical coupling in voltage-gated ion channels.Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating.Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation.Semisynthetic K+ channels show that the constricted conformation of the selectivity filter is not the C-type inactivated state.Recovery from slow inactivation in K+ channels is controlled by water molecules.Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels.Transmembrane allosteric coupling of the gates in a potassium channel.Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating.Modes of glutamate receptor gating.Voltage-Gated Potassium Channels: A Structural Examination of Selectivity and Gating.Discovery and characterisation of a novel toxin from Dendroaspis angusticeps, named Tx7335, that activates the potassium channel KcsA.Exploring the Dynamics of the TWIK-1 Channel.Competing Lipid-Protein and Protein-Protein Interactions Determine Clustering and Gating Patterns in the Potassium Channel from Streptomyces lividans (KcsA).Dynamic water patterns change the stability of the collapsed filter conformation of the KcsA K+ channel.Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation.Complex interactions among residues within pore region determine the K+ dependence of a KAT1-type potassium channel AmKAT1.Probing Conformational Changes during the Gating Cycle of a Potassium Channel in Lipid Bilayers.Site-specific ion occupation in the selectivity filter causes voltage-dependent gating in a viral K+ channel.Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscsCryo-EM structure of the polycystin 2-l1 ion channelMechanisms Underlying the Dual Effect of Polyunsaturated Fatty Acid Analogs on Kv7.1
P2860
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P2860
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
@ast
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
@en
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
@nl
type
label
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
@ast
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
@en
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
@nl
prefLabel
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
@ast
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
@en
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
@nl
P2093
P2860
P1433
P1476
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
@en
P2093
Eduardo Perozo
Julio F Cordero-Morales
Sudha Chakrapani
Vishwanath Jogini
P2860
P304
P356
10.1016/J.BPJ.2011.01.073
P407
P577
2011-05-01T00:00:00Z