Stability assessment on a library scale: a rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc.
about
Engineered IgG1-Fc--one fragment to bind them allTherapeutic antibody engineering by high efficiency cell screening.Creating stable stem regions for loop elongation in Fcabs - insights from combining yeast surface display, in silico loop reconstruction and molecular dynamics simulations.Construction of pH-sensitive Her2-binding IgG1-Fc by directed evolution.A platform for constructing, evaluating, and screening bioconjugates on the yeast surface.Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies.Directed Evolution of Protein Thermal Stability Using Yeast Surface Display.A HER2-specific Modified Fc Fragment (Fcab) Induces Antitumor Effects Through Degradation of HER2 and Apoptosis.Molecular dynamics simulation of the crystallizable fragment of IgG1-insights for the design of FcabsTwo-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 Å crystal structure of the complex.Engineering of Fc Fragments with Optimized Physicochemical Properties Implying Improvement of Clinical Potentials for Fc-Based Therapeutics.
P2860
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P2860
Stability assessment on a library scale: a rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc.
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Stability assessment on a libr ...... of the CH3 domains of IgG1-Fc.
@ast
Stability assessment on a libr ...... of the CH3 domains of IgG1-Fc.
@en
Stability assessment on a libr ...... of the CH3 domains of IgG1-Fc.
@nl
type
label
Stability assessment on a libr ...... of the CH3 domains of IgG1-Fc.
@ast
Stability assessment on a libr ...... of the CH3 domains of IgG1-Fc.
@en
Stability assessment on a libr ...... of the CH3 domains of IgG1-Fc.
@nl
prefLabel
Stability assessment on a libr ...... of the CH3 domains of IgG1-Fc.
@ast
Stability assessment on a libr ...... of the CH3 domains of IgG1-Fc.
@en
Stability assessment on a libr ...... of the CH3 domains of IgG1-Fc.
@nl
P2093
P2860
P50
P356
P1476
Stability assessment on a libr ...... of the CH3 domains of IgG1-Fc.
@en
P2093
Christoph Hasenhindl
Florian Rüker
Gerhard Stadlmayr
Phil C Jones
P2860
P304
P356
10.1093/PROTEIN/GZT041
P577
2013-09-04T00:00:00Z