Conformation of the human immunoglobulin G2 hinge imparts superagonistic properties to immunostimulatory anticancer antibodies.
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Influence of immunoglobulin isotype on therapeutic antibody functionPrinciples of antibody-mediated TNF receptor activationAntiviral Functions of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific IgG Antibodies: Effects of Antiretroviral Therapy and Implications for Therapeutic HIV-1 Vaccine Design.Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies.Enhancing the safety of antibody-based immunomodulatory cancer therapy without compromising therapeutic benefit: Can we have our cake and eat it too?Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement.Immuno-regulatory antibodies for the treatment of cancer.FcγR requirements leading to successful immunotherapy.Discovery and bio-optimization of human antibody therapeutics using the XenoMouse® transgenic mouse platform.Regulation of Monoclonal Antibody Immunotherapy by FcγRIIB.Harnessing co-stimulatory TNF receptors for cancer immunotherapy: Current approaches and future opportunities.Cancer immunotherapy: activating innate and adaptive immunity through CD40 agonists.Improving therapeutic activity of anti-CD20 antibody therapy through immunomodulation in lymphoid malignancies.Reformatting Rituximab into Human IgG2 and IgG4 Isotypes Dramatically Improves Apoptosis Induction In Vitro.Improving Antibody-Based Cancer Therapeutics Through Glycan Engineering.Fc Engineering Approaches to Enhance the Agonism and Effector Functions of an Anti-OX40 Antibody.Translating Inhibitory Fc Receptor Biology into Novel Therapeutic Approaches.Special Conference on Tumor Immunology and Immunotherapy: A New Chapter.Rethinking the INN system for therapeutic antibodies.Antibody Isotypes for Tumor Immunotherapy.CIMT 2016: Mechanisms of efficacy in cancer immunotherapy - Report on the 14th Annual Meeting of the Association for Cancer Immunotherapy May 10-12 2016, Mainz, Germany.Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications.Tethered-variable CL bispecific IgG: an antibody platform for rapid bispecific antibody screening.Productive common light chain libraries yield diverse panels of high affinity bispecific antibodies.Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies.Immune Checkpoints as Therapeutic Targets in Autoimmunity
P2860
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P2860
Conformation of the human immunoglobulin G2 hinge imparts superagonistic properties to immunostimulatory anticancer antibodies.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Conformation of the human immu ...... ulatory anticancer antibodies.
@ast
Conformation of the human immu ...... ulatory anticancer antibodies.
@en
Conformation of the human immu ...... ulatory anticancer antibodies.
@nl
type
label
Conformation of the human immu ...... ulatory anticancer antibodies.
@ast
Conformation of the human immu ...... ulatory anticancer antibodies.
@en
Conformation of the human immu ...... ulatory anticancer antibodies.
@nl
prefLabel
Conformation of the human immu ...... ulatory anticancer antibodies.
@ast
Conformation of the human immu ...... ulatory anticancer antibodies.
@en
Conformation of the human immu ...... ulatory anticancer antibodies.
@nl
P2093
P2860
P1433
P1476
Conformation of the human immu ...... mulatory anticancer antibodies
@en
P2093
Ali Roghanian
Ann L White
Aymen Al-Shamkhani
C Ian Mockridge
Christine A Penfold
Elizabeth A Potter
H T Claude Chan
J Sjef Verbeek
Jane Willoughby
P2860
P304
P356
10.1016/J.CCELL.2014.11.001
P577
2014-12-11T00:00:00Z