Autotaxin and LPA1 and LPA5 receptors exert disparate functions in tumor cells versus the host tissue microenvironment in melanoma invasion and metastasis - Wikidata - wikimedia - TriplyDB

Autotaxin and LPA1 and LPA5 receptors exert disparate functions in tumor cells versus the host tissue microenvironment in melanoma invasion and metastasis

Autotaxin and LPA1 and LPA5 receptors exert disparate functions in tumor cells versus the host tissue microenvironment in melanoma invasion and metastasis

http://www.wikidata.org/entity/Q34980426

about

Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivo G-Protein-Coupled Lysophosphatidic Acid Receptors and Their Regulation of AKT Signaling Lipid phosphate phosphatases and their roles in mammalian physiology and pathology Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life Uncovering unique roles of LPA receptors in the tumor microenvironment.The autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair.Destabilization of Lysophosphatidic Acid Receptor 1 Reduces Cytokine Release and Protects Against Lung Injury.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.Autotaxin inhibitors: a patent review (2012-2016).EDG2 enhanced the progression of hepatocellular carcinoma by LPA/PI3K/AKT/ mTOR signaling.Roles of LPA receptor signaling in breast cancer.Distinct Metabolic features differentiating FLT3-ITD AML from FLT3-WT childhood Acute Myeloid Leukemia.Coming of Age for Autotaxin and Lysophosphatidate Signaling: Clinical Applications for Preventing, Detecting and Targeting Tumor-Promoting Inflammation.Limited fibrosis accompanies triple-negative breast cancer metastasis in multiple model systems and is not a preventive target.Autotaxin in Pathophysiology and Pulmonary Fibrosis.Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders Production of extracellular lysophosphatidic acid in the regulation of adipocyte functions and liver fibrosis Genetic expression profile-based screening of genes and pathways associated with papillary thyroid carcinoma

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P2860

Autotaxin and LPA1 and LPA5 receptors exert disparate functions in tumor cells versus the host tissue microenvironment in melanoma invasion and metastasis

http://www.wikidata.org/entity/Q34980426

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

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2014年論文

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2014年论文

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name

Autotaxin and LPA1 and LPA5 re ...... lanoma invasion and metastasis

@ast

Autotaxin and LPA1 and LPA5 re ...... lanoma invasion and metastasis

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Autotaxin and LPA1 and LPA5 re ...... lanoma invasion and metastasis

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type

label

Autotaxin and LPA1 and LPA5 re ...... lanoma invasion and metastasis

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Autotaxin and LPA1 and LPA5 re ...... lanoma invasion and metastasis

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Autotaxin and LPA1 and LPA5 re ...... lanoma invasion and metastasis

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prefLabel

Autotaxin and LPA1 and LPA5 re ...... lanoma invasion and metastasis

@ast

Autotaxin and LPA1 and LPA5 re ...... lanoma invasion and metastasis

@en

Autotaxin and LPA1 and LPA5 re ...... lanoma invasion and metastasis

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1541-7786.MCR-14-0263

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Molecular Cancer Research

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Autotaxin and LPA1 and LPA5 re ...... lanoma invasion and metastasis

@en

P2093

Christopher M Waters

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Derek D Norman

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Duane D Miller

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Erzsebet Szabo

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Gabor J Tigyi

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Jianxiong Liu

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Junming Yue

http://www.w3.org/2001/XMLSchema#string

Louisa Balazs

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Manik C Ghosh

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Renukadevi Patil

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P2860

Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma

Role of the autotaxin-lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy

LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor

Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

LPA receptors: subtypes and biological actions

Lysophosphatidic acid augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 expression

Microenvironmental regulation of tumor progression and metastasis

Tumor microenvironment complexity: emerging roles in cancer therapy.

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174-185

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scholarly article

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10.1158/1541-7786.MCR-14-0263

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