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Detecting gene-gene interactions that underlie human diseases.

Detecting gene-gene interactions that underlie human diseases.

http://www.wikidata.org/entity/Q34980492

about

Human genetics and genomics a decade after the release of the draft sequence of the human genome Learning genetic epistasis using Bayesian network scoring criteria Considerations for using genetic and epigenetic information in occupational health risk assessment and standard setting Data-driven integration of epidemiological and toxicological data to select candidate interacting genes and environmental factors in association with disease Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report Predictive value of 8 genetic loci for serum uric acid concentration Genetic Susceptibility to Vitiligo: GWAS Approaches for Identifying Vitiligo Susceptibility Genes and Loci A survey about methods dedicated to epistasis detection Statistical analysis for genome-wide association study Epistasis and quantitative traits: using model organisms to study gene-gene interactions From genomes to societies: a holistic view of determinants of human health The advantages and limitations of trait analysis with GWAS: a review Child development and molecular genetics: 14 years later Natural variation in Arabidopsis: from molecular genetics to ecological genomics Innate immune gene polymorphisms in tuberculosis Gene-environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop.Epistasis and immunity: the role of genetic interactions in autoimmune diseases Systems genetics for drug target discovery Pathway-based analysis tools for complex diseases: a review Systems analysis of high-throughput data Identification of QTL for UV-protective eye area pigmentation in cattle by progeny phenotyping and genome-wide association analysis Mapping of Genetic Factors That Elicit Intermale Aggressive Behavior on Mouse Chromosome 15: Intruder Effects and the Complex Genetic Basis UGMDR: a unified conceptual framework for detection of multifactor interactions underlying complex traits.GWIS--model-free, fast and exhaustive search for epistatic interactions in case-control GWAS.Hierarchical modularity and the evolution of genetic interactomes across species.Genetics of Common Antipsychotic-Induced Adverse Effects Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions Additional mechanisms conferring genetic susceptibility to Alzheimer's disease Evaluation of potential novel variations and their interactions related to bipolar disorders: analysis of genome-wide association study data Pervasive cryptic epistasis in molecular evolution Epistatic interaction maps relative to multiple metabolic phenotypes Fitness ranking of individual mutants drives patterns of epistatic interactions in HIV-1 Environmental Interactions and Epistasis Are Revealed in the Proteomic Responses to Complex Stimuli Reappraisal of known malaria resistance loci in a large multicenter study Systems Medicine 2.0: potential benefits of combining electronic health care records with systems science models BOOST: A fast approach to detecting gene-gene interactions in genome-wide case-control studies A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21.Missing heritability and strategies for finding the underlying causes of complex disease Genome-Wide Interaction with Insulin Secretion Loci Reveals Novel Loci for Type 2 Diabetes in African Americans.

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Detecting gene-gene interactions that underlie human diseases.

http://www.wikidata.org/entity/Q34980492

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2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Detecting gene-gene interactions that underlie human diseases.

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Detecting gene-gene interactions that underlie human diseases.

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Detecting gene-gene interactions that underlie human diseases.

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Detecting gene-gene interactions that underlie human diseases.

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Detecting gene-gene interactions that underlie human diseases.

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Detecting gene-gene interactions that underlie human diseases.

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Detecting gene-gene interactions that underlie human diseases.

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Detecting gene-gene interactions that underlie human diseases.

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Nature Reviews Genetics

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Detecting gene-gene interactions that underlie human diseases.

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Heather J Cordell

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Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Genome-wide association study identifies novel breast cancer susceptibility loci

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

Information-theoretic metrics for visualizing gene-environment interactions

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study

PLINK: a tool set for whole-genome association and population-based linkage analyses

Screening large-scale association study data: exploiting interactions using random forests

GPNN: power studies and applications of a neural network method for detecting gene-gene interactions in studies of human disease

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392-404

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10.1038/NRG2579

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