Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development.
about
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesisMST kinases in development and diseaseWnt and planar cell polarity signaling in cystic renal diseaseMembrane trafficking in podocyte health and diseaseThe Hippo-YAP pathway in organ size control and tumorigenesis: an updated versionDiscovery and confirmation of ligand binding specificities of the Schistosoma japonicum polarity protein ScribbleCrumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein ExpandedThe Hippo-YAP signaling pathway and contact inhibition of growth.The role of the Hippo pathway in human disease and tumorigenesisWtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesisMislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancerEstablishment of epithelial polarity--GEF who's minding the GAP?The predominant WT1 isoform (+KTS) encodes a DNA-binding protein targeting the planar cell polarity gene Scribble in renal podocytes.Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signalingDual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein productsThe Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia.YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.Role of the polarity protein Scribble for podocyte differentiation and maintenanceRecurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.Sleeping giants: emerging roles for the fat cadherins in health and disease.The role of angiomotin phosphorylation in the Hippo pathway during preimplantation mouse development.FAT1 cadherin is multiply phosphorylated on its ectodomain but phosphorylation is not catalysed by the four-jointed homologue.FAT1 cadherin acts upstream of Hippo signalling through TAZ to regulate neuronal differentiation.Hippo signaling: growth control and beyond.Pronephric tubulogenesis requires Daam1-mediated planar cell polarity signaling.Negative regulation of Yap during neuronal differentiationTEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors.Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.FAT1 mutations cause a glomerulotubular nephropathyNovel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation.Growth control by committee: intercellular junctions, cell polarity, and the cytoskeleton regulate Hippo signaling.Loss of Cell Adhesion Increases Tumorigenic Potential of Polarity Deficient Scribble Mutant CellsAmotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish.FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/β-catenin signalling.Function and cancer genomics of FAT family genes (review)Yes-associated protein (yap) is required for early embryonic development in zebrafish (danio rerio)Mechanisms that link the oncogenic epithelial-mesenchymal transition to suppression of anoikis.Hippo inactivation feeds tumor-initiating cells.Role of genetic modifiers in an orthologous rat model of ARPKD.
P2860
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P2860
Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Scribble participates in Hippo ...... rafish pronephros development.
@ast
Scribble participates in Hippo ...... rafish pronephros development.
@en
Scribble participates in Hippo ...... rafish pronephros development.
@nl
type
label
Scribble participates in Hippo ...... rafish pronephros development.
@ast
Scribble participates in Hippo ...... rafish pronephros development.
@en
Scribble participates in Hippo ...... rafish pronephros development.
@nl
prefLabel
Scribble participates in Hippo ...... rafish pronephros development.
@ast
Scribble participates in Hippo ...... rafish pronephros development.
@en
Scribble participates in Hippo ...... rafish pronephros development.
@nl
P2093
P2860
P356
P1476
Scribble participates in Hippo ...... rafish pronephros development.
@en
P2093
Björn Hartleben
Christina Engel
Christoph Englert
Christopher Boehlke
E Wolfgang Kuehn
Frank Bollig
Haribaskar Ramachandran
Jean-Remy Courbard
P2860
P304
P356
10.1073/PNAS.0811691106
P407
P577
2009-05-13T00:00:00Z