about
Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts.MicroRNA and epilepsy: profiling, functions and potential clinical applications.Silencing the gene encoding C/EBP homologous protein lessens acute brain injury following ischemia/reperfusionBroad therapeutic benefit after RNAi expression vector delivery to deep cerebellar nuclei: implications for spinocerebellar ataxia type 1 therapyTriplet repeat RNA structure and its role as pathogenic agent and therapeutic targetMutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's diseaseShort-interference RNAs: becoming medicines.Examination of mesenchymal stem cell-mediated RNAi transfer to Huntington's disease affected neuronal cells for reduction of huntingtin.RISC in PD: the impact of microRNAs in Parkinson's disease cellular and molecular pathogenesis.Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis.Engineered antibody therapies to counteract mutant huntingtin and related toxic intracellular proteinsFGFR3 targeting strategies for achondroplasia.Novel siRNA delivery strategy: a new "strand" in CNS translational medicine?Synthetic nucleic acids delivered by exosomes: a potential therapeutic for generelated metabolic brain diseases.Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration.AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington's disease.microRNA and Epilepsy.Remote and reversible inhibition of neurons and circuits by small molecule induced potassium channel stabilization.Design, Characterization, and Lead Selection of Therapeutic miRNAs Targeting Huntingtin for Development of Gene Therapy for Huntington's Disease.Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study.Effects of AAV-mediated knockdown of nNOS and GPx-1 gene expression in rat hippocampus after traumatic brain injury.MicroRNA in neurodegenerative drug discovery: the way forward?Translation of MicroRNA-Based Huntingtin-Lowering Therapies from Preclinical Studies to the Clinic.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
RNAi medicine for the brain: progresses and challenges.
@ast
RNAi medicine for the brain: progresses and challenges.
@en
RNAi medicine for the brain: progresses and challenges.
@nl
type
label
RNAi medicine for the brain: progresses and challenges.
@ast
RNAi medicine for the brain: progresses and challenges.
@en
RNAi medicine for the brain: progresses and challenges.
@nl
prefLabel
RNAi medicine for the brain: progresses and challenges.
@ast
RNAi medicine for the brain: progresses and challenges.
@en
RNAi medicine for the brain: progresses and challenges.
@nl
P2860
P356
P1476
RNAi medicine for the brain: progresses and challenges
@en
P2093
Beverly L Davidson
Edgardo Rodríguez-Lebrón
P2860
P356
10.1093/HMG/DDR137
P577
2011-03-31T00:00:00Z