Human DNA damage response and repair deficiency syndromes: linking genomic instability and cell cycle checkpoint proficiency.
about
Understanding the impact of 1q21.1 copy number variantThe DNA Damage Response: Making It Safe to Play with KnivesIncreased RPA1 gene dosage affects genomic stability potentially contributing to 17p13.3 duplication syndromeTipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.Functional characterization of a cancer causing mutation in human replication protein ATargeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancerDynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activityRad9 interacts with Aft1 to facilitate genome surveillance in fragile genomic sites under non-DNA damage-inducing conditions in S. cerevisiaeIdentification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator AvenWolf-Hirschhorn syndrome candidate 1 is involved in the cellular response to DNA damageATM-dependent phosphorylation of the checkpoint clamp regulates repair pathways and maintains genomic stabilityThe hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivoReplication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathwayIs activation of the intra-S checkpoint in human fibroblasts an important factor in protection against UV-induced mutagenesis?LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors.Beyond ATM: the protein kinase landscape of the DNA damage response.Mind the gap: keeping UV lesions in check.Cancer predisposing mutations in BRCT domains.Mapping genetic alterations causing chemoresistance in cancer: identifying the roads by tracking the drivers.Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis.Repair of double-strand breaks by end joining.DNA Damage Response is Prominent in Ovarian High-Grade Serous Carcinomas, Especially Those with Rsf-1 (HBXAP) Overexpression.Primary microcephaly, impaired DNA replication, and genomic instability caused by compound heterozygous ATR mutations.MCPH1 patient cells exhibit delayed release from DNA damage-induced G2/M checkpoint arrest.USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation.DNA breakage and cell cycle checkpoint abrogation induced by a therapeutic thiopurine and UVA radiationA role for checkpoint kinase-dependent Rad26 phosphorylation in transcription-coupled DNA repair in Saccharomyces cerevisiae.Put a RING on it: regulation and inhibition of RNF8 and RNF168 RING finger E3 ligases at DNA damage sites.A central role of TRAX in the ATM-mediated DNA repair.Glycogen synthase kinase (GSK)-3 and mammalian target of rapamycin complex 1 (mTORC1) cooperate to regulate protein S6 kinase 1 (S6K1).DNA damage response induced by Etoposide promotes steroidogenesis via GADD45A in cultured adrenal cells.
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Human DNA damage response and repair deficiency syndromes: linking genomic instability and cell cycle checkpoint proficiency.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Human DNA damage response and ...... cycle checkpoint proficiency.
@ast
Human DNA damage response and ...... cycle checkpoint proficiency.
@en
Human DNA damage response and ...... cycle checkpoint proficiency.
@nl
type
label
Human DNA damage response and ...... cycle checkpoint proficiency.
@ast
Human DNA damage response and ...... cycle checkpoint proficiency.
@en
Human DNA damage response and ...... cycle checkpoint proficiency.
@nl
prefLabel
Human DNA damage response and ...... cycle checkpoint proficiency.
@ast
Human DNA damage response and ...... cycle checkpoint proficiency.
@en
Human DNA damage response and ...... cycle checkpoint proficiency.
@nl
P1433
P1476
Human DNA damage response and ...... cycle checkpoint proficiency.
@en
P2093
Claudia Kerzendorfer
P304
P356
10.1016/J.DNAREP.2009.04.018
P577
2009-05-26T00:00:00Z