Acquired mutations in TET2 are common in myelodysplastic syndromes. - Wikidata - wikimedia - TriplyDB

Acquired mutations in TET2 are common in myelodysplastic syndromes.

Acquired mutations in TET2 are common in myelodysplastic syndromes.

http://www.wikidata.org/entity/Q34984094

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The epigenetic landscape of acute myeloid leukemia Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases The emerging insights into catalytic or non-catalytic roles of TET proteins in tumors and neural development Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in Disease Epigenetic modulators, modifiers and mediators in cancer aetiology and progression Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes Functions of TET Proteins in Hematopoietic Transformation Towards an understanding of the role of DNA methylation in rheumatoid arthritis: therapeutic and diagnostic implications Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells G17V RHOA: Genetic evidence of GTP-unbound RHOA playing a role in tumorigenesis in T cells Connections between TET proteins and aberrant DNA modification in cancer Molecular prognostic factors in cytogenetically normal acute myeloid leukemia Mechanism and function of oxidative reversal of DNA and RNA methylation The TET2 interactors and their links to hematological malignancies JAK2 and genomic instability in the myeloproliferative neoplasms: a case of the chicken or the egg?Genomic Variants Revealed by Invariably Missing Genotypes in Nelore Cattle Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1 IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis.Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study.Recurrent DNMT3A mutations in patients with myelodysplastic syndromes Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts Integrated molecular analysis of clear-cell renal cell carcinoma.Role of TET enzymes in DNA methylation, development, and cancer DNMT3A and TET2 in the Pre-Leukemic Phase of Hematopoietic Disorders Recent advances in diagnosis, molecular pathology and therapy of chronic myelomonocytic leukaemia Profound parental bias associated with chromosome 14 acquired uniparental disomy indicates targeting of an imprinted locus Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation Intrinsic and extrinsic connections of Tet3 dioxygenase with CXXC zinc finger modules Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies High accuracy mutation detection in leukemia on a selected panel of cancer genes The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing

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Acquired mutations in TET2 are common in myelodysplastic syndromes.

http://www.wikidata.org/entity/Q34984094

description

2009 nî lūn-bûn

@nan

2009 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2009 թվականի մայիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Acquired mutations in TET2 are common in myelodysplastic syndromes.

@ast

Acquired mutations in TET2 are common in myelodysplastic syndromes.

@en

Acquired mutations in TET2 are common in myelodysplastic syndromes.

@nl

type

label

Acquired mutations in TET2 are common in myelodysplastic syndromes.

@ast

Acquired mutations in TET2 are common in myelodysplastic syndromes.

@en

Acquired mutations in TET2 are common in myelodysplastic syndromes.

@nl

prefLabel

Acquired mutations in TET2 are common in myelodysplastic syndromes.

@ast

Acquired mutations in TET2 are common in myelodysplastic syndromes.

@en

Acquired mutations in TET2 are common in myelodysplastic syndromes.

@nl

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Nature Genetics

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Acquired mutations in TET2 are common in myelodysplastic syndromes.

@en

P2093

Ad Geurts van Kessel

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Anne Hagemeijer

http://www.w3.org/2001/XMLSchema#string

Bert A van der Reijden

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Ellen Stevens-Linders

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Estelle Verburgh

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Eveline J Kamping

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Gregor E Verhoef

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Joop H Jansen

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Mariam G Aslanyan

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Marieke Berends

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838-842

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scholarly article

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10.1038/NG.391

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7

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41

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Adrianus Henricus Maria Geurts van Kessel

Peter Vandenberghe

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2009-05-31T00:00:00Z

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26254567

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19483684

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