Identification of serines 201 and 209 as sites of Pax3 phosphorylation and the altered phosphorylation status of Pax3-FOXO1 during early myogenic differentiation.
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Mechanisms contributing to differential regulation of PAX3 downstream target genes in normal human epidermal melanocytes versus melanoma cellsPhosphorylation of PAX3 contributes to melanoma phenotypes by affecting proliferation, invasion, and transformationCyclin-dependent kinase 4 phosphorylates and positively regulates PAX3-FOXO1 in human alveolar rhabdomyosarcoma cellsInhibiting phosphorylation of the oncogenic PAX3-FOXO1 reduces alveolar rhabdomyosarcoma phenotypes identifying novel therapy optionsAKT and PAX3-FKHR cooperation enforces myogenic differentiation blockade in alveolar rhabdomyosarcoma cellCaspase 3 cleavage of Pax7 inhibits self-renewal of satellite cellsGSK-3 promotes cell survival, growth, and PAX3 levels in human melanoma cellsIdentification of CK2 as the kinase that phosphorylates Pax3 at Ser209 in early myogenic differentiationCk2-Dependent Phosphorylation Is Required to Maintain Pax7 Protein Levels in Proliferating Muscle ProgenitorsComparative transcriptomic analysis reveals the oncogenic fusion protein PAX3-FOXO1 globally alters mRNA and miRNA to enhance myoblast invasion.Acquisition of an oncogenic fusion protein serves as an initial driving mutation by inducing aneuploidy and overriding proliferative defects.A call to ARMS: targeting the PAX3-FOXO1 gene in alveolar rhabdomyosarcoma.Melanoma biomolecules: independently identified but functionally intertwined.Acquisition of an oncogenic fusion protein is sufficient to globally alter the landscape of miRNA expression to inhibit myogenic differentiation.
P2860
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P2860
Identification of serines 201 and 209 as sites of Pax3 phosphorylation and the altered phosphorylation status of Pax3-FOXO1 during early myogenic differentiation.
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2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Identification of serines 201 ...... arly myogenic differentiation.
@ast
Identification of serines 201 ...... arly myogenic differentiation.
@en
Identification of serines 201 ...... arly myogenic differentiation.
@nl
type
label
Identification of serines 201 ...... arly myogenic differentiation.
@ast
Identification of serines 201 ...... arly myogenic differentiation.
@en
Identification of serines 201 ...... arly myogenic differentiation.
@nl
prefLabel
Identification of serines 201 ...... arly myogenic differentiation.
@ast
Identification of serines 201 ...... arly myogenic differentiation.
@en
Identification of serines 201 ...... arly myogenic differentiation.
@nl
P2093
P2860
P1476
Identification of serines 201 ...... arly myogenic differentiation.
@en
P2093
Aditi S Iyengar
Andrew D Hollenbach
Jacob M Loupe
Kevin N Dietz
Patrick J Miller
P2860
P304
P356
10.1016/J.BIOCEL.2011.03.010
P577
2011-03-31T00:00:00Z