Ca2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin I - Wikidata - wikimedia - TriplyDB

Ca2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin I

Ca2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin I

http://www.wikidata.org/entity/Q34984621

about

Dynamic Ca2+-dependent stimulation of vesicle fusion by membrane-anchored synaptotagmin 1 Regulation of intracellular membrane trafficking and cell dynamics by syntaxin-6 Lateral diffusion of proteins on supported lipid bilayers: additive friction of synaptotagmin 7 C2A-C2B tandem domains.Structure of human synaptotagmin 1 C2AB in the absence of Ca2+ reveals a novel domain association Molecular mechanism of the synaptotagmin–SNARE interaction in Ca2+-triggered vesicle fusion Cis- and trans-membrane interactions of synaptotagmin-1 Analysis of the synaptotagmin family during reconstituted membrane fusion. Uncovering a class of inhibitory isoforms Ring-like oligomers of Synaptotagmins and related C2 domain proteins The juxtamembrane linker of full-length synaptotagmin 1 controls oligomerization and calcium-dependent membrane binding.The N-terminal domain tethers the voltage-gated calcium channel β2e-subunit to the plasma membrane via electrostatic and hydrophobic interactions Solution and membrane-bound conformations of the tandem C2A and C2B domains of synaptotagmin 1: Evidence for bilayer bridging The calcium-dependent and calcium-independent membrane binding of synaptotagmin 1: two modes of C2B binding.Cross-linking of phospholipid membranes is a conserved property of calcium-sensitive synaptotagmins Interaction of synaptotagmin with lipid bilayers, analyzed by single-molecule force spectroscopy.Myoblast fusion: when it takes more to make one.Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission.Characterization of the lipid binding properties of Otoferlin reveals specific interactions between PI(4,5)P2 and the C2C and C2F domains.Synaptotagmin's role in neurotransmitter release likely involves Ca(2+)-induced conformational transition.The Arabidopsis synaptotagmin SYTA regulates the cell-to-cell movement of diverse plant viruses Rubella virus: first calcium-requiring viral fusion protein.New insights into short-term synaptic facilitation at the frog neuromuscular junction.Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation.Mechanism and function of synaptotagmin-mediated membrane apposition.Calcium binding promotes conformational flexibility of the neuronal Ca(2+) sensor synaptotagmin.Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release.Dysferlin and muscle membrane repair.Different states of synaptotagmin regulate evoked versus spontaneous release.Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+.Genetic analysis of synaptotagmin C2 domain specificity in regulating spontaneous and evoked neurotransmitter release.A time course of orchestrated endophilin action in sensing, bending, and stabilizing curved membranes.Conformational dynamics of calcium-triggered activation of fusion by synaptotagmin.Mutations that disrupt Ca²⁺-binding activity endow Doc2β with novel functional properties during synaptic transmission.Control of membrane gaps by synaptotagmin-Ca2+ measured with a novel membrane distance ruler Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7 Circular oligomerization is an intrinsic property of synaptotagmin.C2-domain containing calcium sensors in neuroendocrine secretion.Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion.Distinct roles of the C2A and the C2B domain of the vesicular Ca2+ sensor synaptotagmin 9 in endocrine beta-cells.

P2860

Q24633121-84591DF8-4F16-43B8-9F51-FC2C874995A4 Q24633280-4112E285-C52B-49D5-A46D-9615829D7D3B Q27339721-32BFF624-DF9D-4601-A8AC-330B7C445065 Q27648873-99A5F22C-C5E1-4D33-B269-85D8CBEF5E14 Q27659974-8031943B-BC8E-43B1-8D13-82DA38BAFFD4 Q28575486-316E3A80-AC37-45C6-A262-28CF1C1D6F04 Q28576116-5E52C1DB-9FBA-4978-8DBB-5C2EE22FBC92 Q28831105-7771D34E-0015-4FF0-A8C9-C3B23D22FAC3 Q30371438-19A6E2FB-AC38-4FA2-B1D0-0E21852EE924 Q30405831-61B26825-CAD6-497E-BCC8-8734F0A34515 Q30435374-2C3537F4-463E-4A6C-BDAD-A1C420A264DE Q30436665-D14D9732-EBAF-436B-A687-CC6BDEF1393B Q33338314-AC5E16CB-C338-4CD7-9B28-F1E9BC1C3650 Q33722877-D89EFA24-E054-49FB-8FFD-C32F283264A7 Q33787549-5CA8A862-7EB5-4E6D-9337-581DF71FD259 Q33961419-414993B2-D34B-488C-BE87-9060DE3C90B9 Q34069969-E61FCCBC-F72E-4ADF-9858-9633181BE016 Q34089077-5C272BAF-4794-44C5-88C0-90DE65472DC9 Q34144056-2E40E32B-29FC-4657-AFDA-42051E55CBD9 Q34462217-E0501DD7-3B68-4E9D-A170-D13E56BCEC5F Q34633762-4710607F-5AE9-414C-9023-2AF8AF14C25C Q34959611-2B300CAD-B10B-4B1D-A790-BDABC7510058 Q35089488-D49FD816-6089-4450-AAAE-FBEAF2FEDEC3 Q35089614-DD17E66B-5D76-4E7B-9B9F-96EDC47841A0 Q35687725-F9865CCB-BFAF-47AB-935E-2017917D417C Q36137565-96CED469-374B-4B7B-9DC8-AA26C7FBD052 Q36282549-63B6BEF2-4543-4CC8-8C5B-23A958E2CC73 Q36719125-F025068B-8CB8-45D1-81C1-6C39DF67CA3A Q36943507-7E6DEE76-855B-4F18-832B-0017BFDC7040 Q37013623-FE1831B4-7A26-4D7B-B158-1C9E13DC1F9C Q37052748-3662C857-FB7E-407E-A6A4-74172CBC27EF Q37368223-9395BA9D-FD49-4CA6-914A-90274C09C987 Q37582539-4C9CEE0E-C5C4-4655-9915-CCF949612833 Q38302250-6E478ED1-C849-43D5-888B-CFD83B22417A Q38321869-5838D855-9430-420C-9E53-A95D53790963 Q38603942-85593664-B1C7-4EFE-8EBE-90DE97BADE16 Q38978762-F3D83EE9-75BC-4B22-B103-873243D35E05 Q40016111-6944C566-292B-4F1C-A858-A2762C888CCA Q40087925-F9997621-444E-40F6-90CC-18253306FC09 Q41774775-D1F39485-4AE2-4C74-B7F4-9E434BFCE4CD

P2860

Ca2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin I

http://www.wikidata.org/entity/Q34984621

description

2006 nî lūn-bûn

@nan

2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年学术文章

@wuu

2006年学术文章

@zh-cn

2006年学术文章

@zh-hans

2006年学术文章

@zh-my

2006年学术文章

@zh-sg

2006年學術文章

@yue

name

Ca2+-triggered simultaneous me ...... C2-domains of synaptotagmin I

@ast

Ca2+-triggered simultaneous me ...... C2-domains of synaptotagmin I

@en

Ca2+-triggered simultaneous me ...... C2-domains of synaptotagmin I

@nl

type

label

Ca2+-triggered simultaneous me ...... C2-domains of synaptotagmin I

@ast

Ca2+-triggered simultaneous me ...... C2-domains of synaptotagmin I

@en

Ca2+-triggered simultaneous me ...... C2-domains of synaptotagmin I

@nl

prefLabel

Ca2+-triggered simultaneous me ...... C2-domains of synaptotagmin I

@ast

Ca2+-triggered simultaneous me ...... C2-domains of synaptotagmin I

@en

Ca2+-triggered simultaneous me ...... C2-domains of synaptotagmin I

@nl

P1433

Q34984621-CA632E7B-908F-40BA-82EA-8E111AB4C076

P1476

Q34984621-367F7249-F087-4C24-8A17-9CCA46AF0DFD

P2093

Q34984621-2AD7F467-0E1A-4302-9B3E-9D33275650C1

Q34984621-38CD82A6-4EB6-42D8-A06A-CFCE0F0816F3

Q34984621-F433D090-C03D-4532-949D-7A4EAFD68536

P2860

Q34984621-02EC4CCD-E056-4FAD-8D30-031DFC784878

Q34984621-0D10D639-4F29-4DD9-9B56-4F1544F9F2E5

Q34984621-0E10DB67-65D2-40B3-BCE6-9BE4A213004E

Q34984621-156CA42A-0E6E-4E53-B63A-A19A4D5710D5

Q34984621-1F7E074F-EC3C-4D62-B7A4-6E3CBF1FB528

Q34984621-215329C4-F19C-4A01-A657-129780DBE1DE

Q34984621-3AECEE5A-3314-4E8F-9E86-2F9D46A00E61

Q34984621-4B265463-F969-40AF-BC64-F855A558CAA4

Q34984621-4F094719-9356-4220-962B-C0212B18B483

Q34984621-5797A5B1-90F8-45C4-B2B2-B4BDAF75E8BC

P304

Q34984621-F7E4448A-4E79-4B28-AD9A-B58F00E3AA21

P31

Q34984621-304764BC-08C5-40FE-B608-F2A6E4557922

P356

Q34984621-4EBA26CA-506E-4439-BAAC-E57F321A0A05

P407

Q34984621-88DEF33A-32A0-4394-A7AF-61F51A36EC27

P433

Q34984621-CD4CACC1-15F1-4FAB-B367-19C60883A4A5

P478

Q34984621-E9B45E1A-BF78-41E7-B5B2-834264DD2A2A

P577

Q34984621-C623905D-4678-49E0-AF26-CD0907BD37FB

P5875

Q34984621-701AC593-E74E-42A5-B401-C2D1DB1B3F4B

P698

Q34984621-66980AB0-400F-4F39-AFC0-A6677795AE40

P932

Q34984621-7674010A-BB4F-4732-9CE3-6C1B545EE64B

P356

BIOPHYSJ.105.080325

P1433

Biophysical Journal

P1476

Ca2+-triggered simultaneous me ...... C2-domains of synaptotagmin I

@en

P2093

Edwin R Chapman

http://www.w3.org/2001/XMLSchema#string

Enfu Hui

http://www.w3.org/2001/XMLSchema#string

Jihong Bai

http://www.w3.org/2001/XMLSchema#string

P2860

Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1

Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction

Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine

Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold

Synaptotagmin I functions as a calcium regulator of release probability

Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis

Synaptotagmin: a Ca(2+) sensor that triggers exocytosis?

A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding

Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

P304

1767-1777

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1529/BIOPHYSJ.105.080325

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

91

http://www.w3.org/2001/XMLSchema#string

P577

2006-06-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7000707

http://www.w3.org/2001/XMLSchema#string

P698

16782782

http://www.w3.org/2001/XMLSchema#string

P932

1544279

http://www.w3.org/2001/XMLSchema#string