The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association
about
The cell surface environment for pathogen recognition and entryPhospholipase D1 and choline kinase-α are interactive targets in breast cancer.CSF-1 receptor signaling in myeloid cellsPhospholipase D in cell signaling: from a myriad of cell functions to cancer growth and metastasis.Phospholipase D facilitates efficient entry of influenza virus, allowing escape from innate immune inhibitionMyeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infectionA river runs through it: how autophagy, senescence, and phagocytosis could be linked to phospholipase D by Wnt signalingThe molecular basis of leukocyte adhesion involving phosphatidic acid and phospholipase DDeficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment.Chloride channel-3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survival.The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).Biochemical and cellular implications of a dual lipase-GEF function of phospholipase D2 (PLD2).A GEF-to-phospholipase molecular switch caused by phosphatidic acid, Rac and JAK tyrosine kinase that explains leukocyte cell migrationMacrophage migration arrest due to a winning balance of Rac2/Sp1 repression over β-catenin-induced PLD expressionPhospholipase D (PLD) drives cell invasion, tumor growth and metastasis in a human breast cancer xenograph model.Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease.Growth factor receptor-bound protein 2 contributes to (hem)immunoreceptor tyrosine-based activation motif-mediated signaling in platelets.Intracellular targeting of annexin A2 inhibits tumor cell adhesion, migration, and in vivo grafting.Epidermal growth factor receptors containing a single tyrosine in their C-terminal tail bind different effector molecules and are signaling-competent.Systems Analysis of the Liver Transcriptome in Adult Male Zebrafish Exposed to the Plasticizer (2-Ethylhexyl) Phthalate (DEHP).An integrative toy model of cell flattening, spreading, and ruffling.Oxidized LDL phagocytosis during foam cell formation in atherosclerotic plaques relies on a PLD2-CD36 functional interdependence.GRAMD1B regulates cell migration in breast cancer cells through JAK/STAT and Akt signaling.
P2860
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P2860
The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The mechanism of cell membrane ...... D2), Grb2 and Rac2 association
@ast
The mechanism of cell membrane ...... D2), Grb2 and Rac2 association
@en
The mechanism of cell membrane ...... D2), Grb2 and Rac2 association
@nl
type
label
The mechanism of cell membrane ...... D2), Grb2 and Rac2 association
@ast
The mechanism of cell membrane ...... D2), Grb2 and Rac2 association
@en
The mechanism of cell membrane ...... D2), Grb2 and Rac2 association
@nl
prefLabel
The mechanism of cell membrane ...... D2), Grb2 and Rac2 association
@ast
The mechanism of cell membrane ...... D2), Grb2 and Rac2 association
@en
The mechanism of cell membrane ...... D2), Grb2 and Rac2 association
@nl
P2093
P2860
P1433
P1476
The mechanism of cell membrane ...... D2), Grb2 and Rac2 association
@en
P2093
Dianne Cox
Hong-Juan Peng
Julian Gomez-Cambronero
Madhu Mahankali
P2860
P304
P356
10.1016/J.CELLSIG.2011.03.010
P577
2011-03-16T00:00:00Z