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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

Paradoxical relationship between chromosomal instability and survival outcome in cancer.

http://www.wikidata.org/entity/Q34988001

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Intratumor heterogeneity: evolution through space and time Chromosomal instability and cancer: a complex relationship with therapeutic potential Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine Tumor heterogeneity and resistance to EGFR-targeted therapy in advanced nonsmall cell lung cancer: challenges and perspectives Promoter Hypermethylation of FANCF and Susceptibility and Prognosis of Epithelial Ovarian Cancer An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development Can oncology recapitulate paleontology? Lessons from species extinctions The causes and consequences of genetic heterogeneity in cancer evolution Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer The temporal dynamics of chromosome instability in ovarian cancer cell lines and primary patient samples.The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma.Cancer chromosomal instability: therapeutic and diagnostic challenges.Karyotypic determinants of chromosome instability in aneuploid budding yeast.Cancer heterogeneity: implications for targeted therapeutics.Luminal A and luminal B (HER2 negative) subtypes of breast cancer consist of a mixture of tumors with different genotype.Molecular characterisation of isogenic taxane resistant cell lines identify novel drivers of drug resistance.Profiles of genomic instability in high-grade serous ovarian cancer predict treatment outcome Tug-of-war between driver and passenger mutations in cancer and other adaptive processes High levels of genomic aberrations in serous ovarian cancers are associated with better survival.Biomolecular events in cancer revealed by attractor metagenes.The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer.Genomic instability: a stronger prognostic marker than proliferation for early stage luminal breast carcinomas.Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer Chromosomal instability as a prognostic marker in cervical cancer.Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma.A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables.Aneuploidy and chromosomal instability in cancer: a jackpot to chaos.APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity.Losing balance: the origin and impact of aneuploidy in cancer Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas.Transcriptional consequences of aneuploidy.Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.Centromere protein-A, an essential centromere protein, is a prognostic marker for relapse in estrogen receptor-positive breast cancer Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability.Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork.A robust prognostic gene expression signature for early stage lung adenocarcinoma.Impact of deleterious passenger mutations on cancer progression.Aneuploidy in health, disease, and aging.The gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition.

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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

http://www.wikidata.org/entity/Q34988001

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2011 nî lūn-bûn

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Paradoxical relationship between chromosomal instability and survival outcome in cancer.

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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

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0008-5472.CAN-10-3667

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Cancer Research

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Paradoxical relationship between chromosomal instability and survival outcome in cancer.

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Andrea L Richardson

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David Endesfelder

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Iain B Tan

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Patrick Tan

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Qiyuan Li

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Sarah E McClelland

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P2860

Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts.

Molecular portraits of human breast tumours

Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer

Genes that mediate breast cancer metastasis to lung

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis

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10.1158/0008-5472.CAN-10-3667

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10

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71

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Aron Charles Eklund

Zoltan Szallasi

Charles Swanton

Nicolai J Birkbak

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2011-01-26T00:00:00Z

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21270108

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3096721

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