Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21. - Wikidata - wikimedia - TriplyDB

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

http://www.wikidata.org/entity/Q34988091

about

Radiation enteropathy--pathogenesis, treatment and prevention A novel radioprotective function for the mitochondrial tumor suppressor protein Fus1 The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA.Krüppel-like factor 4 is a radioprotective factor for the intestine following γ-radiation-induced gut injury in mice.Laser capture microdissected mucosa versus whole tissue specimens for assessment of radiation-induced dynamic molecular and pathway changes in the small intestine PUMA Cooperates with p21 to Regulate Mammary Epithelial Morphogenesis and Epithelial-To-Mesenchymal Transition.Depending on the stage of hepatosteatosis, p53 causes apoptosis primarily through either DRAM-induced autophagy or BAX.The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest.Ionizing irradiation induces acute haematopoietic syndrome and gastrointestinal syndrome independently in mice.Transcriptional corepressor MTG16 regulates small intestinal crypt proliferation and crypt regeneration after radiation-induced injury PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation The p53-PUMA axis suppresses iPSC generation p21 protects "Super p53" mice from the radiation-induced gastrointestinal syndrome.Epidermal growth factor regulates hematopoietic regeneration after radiation injury Assessing the radiation response of lung cancer with different gene mutations using genetically engineered mice.Crizotinib induces PUMA-dependent apoptosis in colon cancer cells.Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax.β-Arrestin-2 modulates radiation-induced intestinal crypt progenitor/stem cell injury.Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice.An amino acid-based oral rehydration solution (AA-ORS) enhanced intestinal epithelial proliferation in mice exposed to radiation.Strategies for optimizing the response of cancer and normal tissues to radiation.MicroRNA-17-5p regulated apoptosis-related protein expression and radiosensitivity in oral squamous cell carcinoma caused by betel nut chewing.Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation.Role of p53 in Anticancer Drug Treatment- and Radiation-Induced Injury in Normal Small Intestine.Role of p53 in regulating tissue response to radiation by mechanisms independent of apoptosis.Intestinal stem cell injury and protection during cancer therapy The Evaluation and Comparison of Transcriptionally Targeted Noxa and Puma Killer Genes to Initiate Apoptosis Under Cancer-Specific Promoter CXCR1 in Hepatocarcinoma Gene Therapy Reducing radiation-induced gastrointestinal toxicity - the role of the PHD/HIF axis.Role of Bax/Bcl-2 family members in green tea polyphenol induced necroptosis of p53-deficient Hep3B cells.MicroRNA-17-5p post-transcriptionally regulates p21 expression in irradiated betel quid chewing-related oral squamous cell carcinoma cells.Functional exploration of colorectal cancer genomes using Drosophila.ADAR1 is essential for intestinal homeostasis and stem cell maintenance.Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.Paradoxical Roles of Elongation Factor-2 Kinase in Stem Cell Survival GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome.An apoptosis-independent role of SMAC in tumor suppression Using genetically engineered mice for radiation research.The Trp53-Trp53inp1-Tnfrsf10b pathway regulates the radiation response of mouse spermatogonial stem cells.Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage.

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P2860

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

http://www.wikidata.org/entity/Q34988091

description

2011 nî lūn-bûn

@nan

2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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name

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

@ast

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

@en

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

@nl

type

label

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

@ast

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

@en

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

@nl

prefLabel

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

@ast

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

@en

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.

@nl

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1541-7786.MCR-11-0052

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Molecular Cancer Research

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Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21

@en

P2093

Brian J Leibowitz

http://www.w3.org/2001/XMLSchema#string

Hongtao Liu

http://www.w3.org/2001/XMLSchema#string

Tao Cheng

http://www.w3.org/2001/XMLSchema#string

Wei Qiu

http://www.w3.org/2001/XMLSchema#string

P2860

PUMA induces the rapid apoptosis of colorectal cancer cells

PUMA, a novel proapoptotic gene, is induced by p53

PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome

PUMA, a potent killer with or without p53

p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusion

CDK inhibitors: positive and negative regulators of G1-phase progression

Surfing the p53 network

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616-625

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scholarly article

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10.1158/1541-7786.MCR-11-0052

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5

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9

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2011-03-30T00:00:00Z

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21450905

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3096742

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