A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity.
about
Cancer pharmacogenomics: strategies and challengesDeveloping interventions for cancer-related cognitive dysfunction in childhood cancer survivorsUsing germline genomics to individualize pediatric cancer treatmentsAn eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers.Genetically InFormed therapies--a "GIFT" for children with cancerPolymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia.Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human lymphoblastoid cell lines (LCLs)Metabolomics of the tumor microenvironment in pediatric acute lymphoblastic leukemia.Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translationATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia.Genetic architecture of microRNA expression: implications for the transcriptome and complex traits.Relating human genetic variation to variation in drug responses.Amino acid auxotrophy as a system of immunological control nodes.Genetic and epigenetic variants contributing to clofarabine cytotoxicity.Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and asparaginase induced hepatotoxicity in adult patients with acute lymphoblastic leukemia.Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach.Cancer cell metabolism: one hallmark, many faces.Impact of genetic polymorphisms on chemotherapy toxicity in childhood acute lymphoblastic leukemia.Pharmacogenetic considerations for acute lymphoblastic leukemia therapies.Pharmacogenetics of childhood acute lymphoblastic leukemia.Evaluating the role of admixture in cancer therapy via in vitro drug response and multivariate genome-wide associations.Identification of a cytogenetic and molecular subgroup of acute myeloid leukemias showing sensitivity to L-Asparaginase.Systematic review of pharmacogenomics and adverse drug reactions in paediatric oncology patients.A novel L-asparaginase with low L-glutaminase coactivity is highly efficacious against both T and B cell acute lymphoblastic leukemias in vivo.Clinical impact of in vitro cellular drug resistance on childhood acute lymphoblastic leukemia in Taiwan.Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response
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P2860
A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A genome-wide approach identif ...... s to asparaginase sensitivity.
@ast
A genome-wide approach identif ...... s to asparaginase sensitivity.
@en
A genome-wide approach identif ...... s to asparaginase sensitivity.
@nl
type
label
A genome-wide approach identif ...... s to asparaginase sensitivity.
@ast
A genome-wide approach identif ...... s to asparaginase sensitivity.
@en
A genome-wide approach identif ...... s to asparaginase sensitivity.
@nl
prefLabel
A genome-wide approach identif ...... s to asparaginase sensitivity.
@ast
A genome-wide approach identif ...... s to asparaginase sensitivity.
@en
A genome-wide approach identif ...... s to asparaginase sensitivity.
@nl
P2093
P2860
P356
P1433
P1476
A genome-wide approach identif ...... es to asparaginase sensitivity
@en
P2093
M V Relling
P2860
P2888
P356
10.1038/LEU.2010.256
P577
2010-11-12T00:00:00Z
P5875
P6179
1006589080