The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
about
Concerning RNA-guided gene drives for the alteration of wild populationsHeritable strategies for controlling insect vectors of diseaseDevelopment of synthetic selfish elements based on modular nucleases in Drosophila melanogaster.Massively parallel determination and modeling of endonuclease substrate specificityThe Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.Programmable Genome Editing Tools and their Regulation for Efficient Genome Engineering.Requirements for Driving Antipathogen Effector Genes into Populations of Disease Vectors by Homing.Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations.Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses.Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.Homing endonucleases from mobile group I introns: discovery to genome engineering.Crystallographic analyses illustrate significant plasticity and efficient recoding of meganuclease target specificity.The promise and peril of CRISPR gene drives: Genetic variation and inbreeding may impede the propagation of gene drives based on the CRISPR genome editing technology.Gene Drive: Evolved and Synthetic.Three new active members of the I-OnuI family of homing endonucleases.Engineering altered protein-DNA recognition specificity.
P2860
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P2860
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
@ast
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
@en
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
@nl
type
label
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
@ast
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
@en
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
@nl
prefLabel
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
@ast
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
@en
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
@nl
P2093
P2860
P1433
P1476
The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive
@en
P2093
Barry L Stoddard
Jordan Jarjour
Ryo Takeuchi
Steven Russell
Yuk-Sang Chan
P2860
P304
P356
10.1371/JOURNAL.PONE.0074254
P407
P50
P577
2013-09-10T00:00:00Z