Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
about
Co-Stimulatory Blockade of the CD28/CD80-86/CTLA-4 Balance in Transplantation: Impact on Memory T Cells?Viewing transplantation immunology through today's lens: new models, new imaging, and new insights.Current state of renal transplant immunosuppression: Present and futureTransplantation tolerance and its outcome during infections and inflammationConcordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: cell surface targetsThe CD8 T-cell response during tolerance induction in liver transplantationThe future direction and unmet needs of transplant immunosuppression.Central memory CD8+ T lymphocytes mediate lung allograft acceptance.Pathogen Stimulation History Impacts Donor-Specific CD8(+) T Cell Susceptibility to Costimulation/Integrin Blockade-Based TherapyMemory T-cell-specific therapeutics in organ transplantation.Regulatory dendritic cell infusion prolongs kidney allograft survival in nonhuman primates.T-cell co-stimulatory blockade in kidney transplantation: back to the benchAlefacept promotes immunosuppression-free renal allograft survival in nonhuman primates via depletion of recipient memory T cells.Gazing into a crystal ball to predict kidney transplant outcome.Neutralizing BAFF/APRIL with atacicept prevents early DSA formation and AMR development in T cell depletion induced nonhuman primate AMR model.Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression.Costimulatory pathways in transplantation.Belatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion.LFA-1-specific therapy prolongs allograft survival in rhesus macaques.The allo- and viral-specific immunosuppressive effect of belatacept, but not tacrolimus, attenuates with progressive T cell maturationGVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppressionHeterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection.Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism.Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primatesT cells in the control of organ-specific autoimmunityHeterogeneity within T Cell Memory: Implications for Transplant ToleranceDown-Regulation of Surface CD28 under Belatacept Treatment: An Escape Mechanism for Antigen-Reactive T-CellsAlternative immunomodulatory strategies for xenotransplantation: CD40/154 pathway-sparing regimens promote xenograft survival.Evidence for kidney rejection after combined bone marrow and renal transplantation despite ongoing whole-blood chimerism in rhesus macaques.Overcoming the memory barrier in tolerance induction: molecular mimicry and functional heterogeneity among pathogen-specific T-cell populations.Regulatory T cells exhibit decreased proliferation but enhanced suppression after pulsing with sirolimus.Nonhuman primate transplant models finally evolve: detailed immunogenetic analysis creates new models and strengthens the old.Belatacept and sirolimus prolong nonhuman primate islet allograft survival: adverse consequences of concomitant alefacept therapyEnhanced de novo alloantibody and antibody-mediated injury in rhesus macaques.Blocking MHC class II on human endothelium mitigates acute rejectionPostdepletion Lymphocyte Reconstitution During Belatacept and Rapamycin Treatment in Kidney Transplant Recipients.Can We Repurpose FDA-Approved Alefacept to Diminish the HIV Reservoir?Roles of CD48 in regulating immunity and tolerance.CD57(+) CD4 T Cells Underlie Belatacept-Resistant Allograft RejectionTargeting regulatory T cells in the treatment of type 1 diabetes mellitus.
P2860
Q26796099-8AAF6E1A-717B-4C1C-93D5-DDB89965ED41Q26824352-450777E2-C052-417E-B796-A16D4FB3DDFCQ26829789-6102C01A-60FD-417E-8AB7-4756F580D4C1Q26829817-13F37699-A94E-4D98-A30F-3F47CD4DCFD3Q26830569-1F88DABA-F911-45CC-BB77-8DA6246AC328Q28079184-1B40B77F-187D-47BB-9E7F-F140571DCE68Q30277037-C7FA9ADD-B901-4C61-9080-AB70E07F4902Q30573064-233A02FE-C342-4CE0-9A87-D6B1E6FFC51FQ33636211-EA1B8F87-D4B4-46B3-BE31-667796A02B84Q33708195-B79F8C48-3595-4EE2-BF17-CE5F114EBADAQ33804736-934ACBEA-A281-4049-9567-6D38980FA7A0Q33873078-6726F2F9-C784-41F9-B676-9838F81C4714Q33881015-B3D443C1-4C80-4DAF-B437-B1A326D48775Q33882966-37953251-1B01-4808-B21C-F8F70F71A36DQ33891669-132A0AB9-7D6B-4250-8848-1779888597E6Q34149246-D6C13988-C4C9-47F2-9A24-508040F9B47CQ34187594-D8837F99-B6E9-4288-9C0C-9CF370570BE6Q34322116-6B5A2ABA-71BE-4877-AB60-7CC6239FED7EQ34364120-1ADBD06F-8669-428F-88FF-2C51468E59CAQ34400561-002DADD6-F39B-40E3-B39C-8DE7E674765DQ34450497-3A9FC4A0-A9D1-4B79-B6A8-60520416771EQ34937146-3948F7C2-DC73-4126-A39B-53083F654023Q35149926-A9C532BC-B454-483A-BF05-F17D95305EF3Q35680600-D115C72B-3C4E-4259-AE61-D0BC384134AFQ35836118-8574CFCC-EEBB-42A2-B0E3-B0475B775B8EQ35927610-33FF00F9-7C22-48A9-A12C-85501E1388A5Q35937227-9D8AB10C-5E63-425F-B82C-9F2890BD7382Q36069451-60BB023F-4080-4674-BBF5-5FC497EB052BQ36069536-E36CA50A-9B56-4FDF-95C4-859061E4337BQ36273291-D6ABC1B9-2FA0-467D-9697-8DF246DDBD81Q36316613-355A3FB4-7833-4FF7-9D93-8A04E46DB422Q36351343-017E985F-D8B1-4A51-ADFE-D7B972D90E8FQ36572728-FA1D9223-6EB4-45E1-B1B4-0E6F3BB418B1Q36575860-3C6CF27E-BCC1-4D83-8DD0-6E3070B738F6Q36588477-AC04B2E0-51C3-4C0B-9180-1D09EC019E2EQ36769110-416F3DEB-154C-4DD8-96F4-1FD24D716146Q36827134-3D4EF21C-055B-486A-BFA9-C41E88696A43Q36883146-2D32ACD6-1083-48AA-A7AB-3E9839F6C912Q36901437-D7122825-991E-430B-BAF9-A9D9DA5320C2Q37006155-4845F4C4-7C15-4AEF-A680-EF25A4AF6762
P2860
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
@ast
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
@en
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
@nl
type
label
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
@ast
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
@en
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
@nl
prefLabel
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
@ast
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
@en
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
@nl
P2093
P2860
P356
P1433
P1476
Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
@en
P2093
Alexandra P Turner
Ali H Charafeddine
Allan D Kirk
Avinash Agarwal
Christian P Larsen
Frank V Leopardi
Linda Stempora
Maria Russell
Mingqing Song
Robert L Kampen
P2860
P2888
P304
P356
10.1038/NM.1993
P407
P577
2009-07-05T00:00:00Z