Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions. - Wikidata - wikimedia - TriplyDB

Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions.

Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions.

http://www.wikidata.org/entity/Q34992989

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Concerning immune synapses: a spatiotemporal timeline Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation.Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells.The final steps of integrin activation: the end game A role of kindlin-3 in integrin αMβ2 outside-in signaling and the Syk-Vav1-Rac1/Cdc42 signaling axis Molecular architecture and function of matrix adhesions.Regulation and Function of the RasGRP Family of Ras Activators in Blood Cells Beta1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation.Contact-dependent T cell activation and T cell stopping require talin1 Hematologically important mutations: leukocyte adhesion deficiency (first update).Recent insights into the pathobiology of innate immune deficiencies Integrin associated proteins differentially regulate neutrophil polarity and directed migration in 2D and 3D Leukocyte adhesion deficiency-I variant syndrome (LAD-Iv, LAD-III): molecular characterization of the defect in an index family Lessons from rare maladies: leukocyte adhesion deficiency syndromes.Novel aspects of Kindlin-3 function in humans based on a new case of leukocyte adhesion deficiency III.Kindlin-3 Is Essential for the Resting α4β1 Integrin-mediated Firm Cell Adhesion under Shear Flow Conditions Leukocyte arrest: Biomechanics and molecular mechanisms of β2 integrin activation Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity.The mechanism of kindlin-mediated activation of integrin αIIbβ3.The insider's guide to leukocyte integrin signalling and function.Neutrophil arrest by LFA-1 activation Mechanisms of talin-dependent integrin signaling and crosstalk The central role of the cytoskeleton in mechanisms and functions of the NK cell immune synapse.Talin and kindlin: the one-two punch in integrin activation.Adaptor regulation of LFA-1 signaling in T lymphocyte migration: Potential druggable targets for immunotherapies?Intracellular signalling during neutrophil recruitment.Positive and negative regulation by SLP-76/ADAP and Pyk2 of chemokine-stimulated T-lymphocyte adhesion mediated by integrin α4β1 Complement Receptors in Myeloid Cell Adhesion and Phagocytosis.Expression of kindlin-3 in melanoma cells impedes cell migration and metastasis.Kindlin-3 mediates integrin αLβ2 outside-in signaling, and it interacts with scaffold protein receptor for activated-C kinase 1 (RACK1).The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow.The β2 integrin-kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo.Chemokines and the signaling modules regulating integrin affinity.Novel automated tracking analysis of particles subjected to shear flow: kindlin-3 role in B cells.Signaling and Dynamics of Activation of LFA-1 and Mac-1 by Immobilized IL-8.In vivo adhesion of malignant B cells to bone marrow microvasculature is regulated by α4β1 cytoplasmic-binding proteins.Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus

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Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions.

http://www.wikidata.org/entity/Q34992989

description

2009 nî lūn-bûn

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2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.

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Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.

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Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.

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Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.

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Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.

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Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.

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Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.

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Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.

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Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.

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Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.

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Adi Mory

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Alain Bernard

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Amos Etzioni

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Eugenia Manevich-Mendelson

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Maria Alessandra Rosenthal-Allieri

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Markus Moser

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Memet Aker

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Ronen Alon

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Sara Sebnem Kilic

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2344-2353

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scholarly article

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10.1182/BLOOD-2009-04-218636

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