Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions.
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Concerning immune synapses: a spatiotemporal timelineDistinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation.Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells.The final steps of integrin activation: the end gameA role of kindlin-3 in integrin αMβ2 outside-in signaling and the Syk-Vav1-Rac1/Cdc42 signaling axisMolecular architecture and function of matrix adhesions.Regulation and Function of the RasGRP Family of Ras Activators in Blood CellsBeta1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation.Contact-dependent T cell activation and T cell stopping require talin1Hematologically important mutations: leukocyte adhesion deficiency (first update).Recent insights into the pathobiology of innate immune deficienciesIntegrin associated proteins differentially regulate neutrophil polarity and directed migration in 2D and 3DLeukocyte adhesion deficiency-I variant syndrome (LAD-Iv, LAD-III): molecular characterization of the defect in an index familyLessons from rare maladies: leukocyte adhesion deficiency syndromes.Novel aspects of Kindlin-3 function in humans based on a new case of leukocyte adhesion deficiency III.Kindlin-3 Is Essential for the Resting α4β1 Integrin-mediated Firm Cell Adhesion under Shear Flow ConditionsLeukocyte arrest: Biomechanics and molecular mechanisms of β2 integrin activationHuman immunodeficiency syndromes affecting human natural killer cell cytolytic activity.The mechanism of kindlin-mediated activation of integrin αIIbβ3.The insider's guide to leukocyte integrin signalling and function.Neutrophil arrest by LFA-1 activationMechanisms of talin-dependent integrin signaling and crosstalkThe central role of the cytoskeleton in mechanisms and functions of the NK cell immune synapse.Talin and kindlin: the one-two punch in integrin activation.Adaptor regulation of LFA-1 signaling in T lymphocyte migration: Potential druggable targets for immunotherapies?Intracellular signalling during neutrophil recruitment.Positive and negative regulation by SLP-76/ADAP and Pyk2 of chemokine-stimulated T-lymphocyte adhesion mediated by integrin α4β1Complement Receptors in Myeloid Cell Adhesion and Phagocytosis.Expression of kindlin-3 in melanoma cells impedes cell migration and metastasis.Kindlin-3 mediates integrin αLβ2 outside-in signaling, and it interacts with scaffold protein receptor for activated-C kinase 1 (RACK1).The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow.The β2 integrin-kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo.Chemokines and the signaling modules regulating integrin affinity.Novel automated tracking analysis of particles subjected to shear flow: kindlin-3 role in B cells.Signaling and Dynamics of Activation of LFA-1 and Mac-1 by Immobilized IL-8.In vivo adhesion of malignant B cells to bone marrow microvasculature is regulated by α4β1 cytoplasmic-binding proteins.Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus
P2860
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P2860
Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.
@ast
Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.
@en
Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.
@nl
type
label
Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.
@ast
Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.
@en
Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.
@nl
prefLabel
Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.
@ast
Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.
@en
Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.
@nl
P2093
P1433
P1476
Loss of Kindlin-3 in LAD-III e ...... d under shear flow conditions.
@en
P2093
Alain Bernard
Amos Etzioni
Eugenia Manevich-Mendelson
Maria Alessandra Rosenthal-Allieri
Markus Moser
Memet Aker
Ronen Alon
Ronit Pasvolsky
Sara Sebnem Kilic
P304
P356
10.1182/BLOOD-2009-04-218636
P407
P577
2009-07-17T00:00:00Z